Dermatophytosis Caused by Trichophyton indotineae (Trichophyton mentagrophytes ITS Genotype VIII) in Sri Lanka.


Journal

The American journal of tropical medicine and hygiene
ISSN: 1476-1645
Titre abrégé: Am J Trop Med Hyg
Pays: United States
ID NLM: 0370507

Informations de publication

Date de publication:
09 Jul 2024
Historique:
received: 14 01 2024
accepted: 27 03 2024
medline: 10 7 2024
pubmed: 10 7 2024
entrez: 9 7 2024
Statut: aheadofprint

Résumé

Over the past few years, a recalcitrant dermatophytosis has been observed on the Indian subcontinent, including Sri Lanka, which has caused a major public health issue in the region. An emerging species, Trichophyton indotineae, first described as Trichophyton mentagrophytes ITS genotype VIII, is thought to be responsible for this fast-spreading, mostly terbinafine-resistant dermatophytosis. Recalcitrant dermatophytosis is a challenge to dermatologists, and knowing the causative species and antifungal sensitivity in the earlier stage of management would be invaluable. We report a case series of patients with dermatophytosis caused by T. indotineae in Sri Lanka. This is the first detection of this highly terbinafine-resistant strain in Sri Lanka, and existence of this species should be taken seriously by dermatologists and healthcare policymakers for better management of tinea infections and antifungal stewardship in the country.

Identifiants

pubmed: 38981494
doi: 10.4269/ajtmh.24-0027
pii: tpmd240027
doi:
pii:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Nayani P Madarasingha (NP)

Colombo East Base Hospital, Colombo, Sri Lanka.

Harshini Thabrew (H)

Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.

Silk Uhrlass (S)

Laboport Medical Laboratories, Leipzig-Mölbis, Germany.

Surammika Eriyagama (S)

Base Hospital, Nawalapitiya, Sri Lanka.

Dieter Reinal (D)

Office for Mycology and Tropical Dermatology, Hamburg, Germany.

Primali I Jayasekera (PI)

Medical Research Institute, Colombo, Sri Lanka.

Pietro Nenoff (P)

Laboport Medical Laboratories, Leipzig-Mölbis, Germany.

Classifications MeSH