Prevalence of intestinal protozoan parasites among Asian schoolchildren: a systematic review and meta-analysis.

Asia Intestinal protozoan parasites Meta-analysis Prevalence Schoolchildren

Journal

Infection
ISSN: 1439-0973
Titre abrégé: Infection
Pays: Germany
ID NLM: 0365307

Informations de publication

Date de publication:
09 Jul 2024
Historique:
received: 25 11 2023
accepted: 30 06 2024
medline: 10 7 2024
pubmed: 10 7 2024
entrez: 9 7 2024
Statut: aheadofprint

Résumé

Intestinal protozoan parasites among Asian schoolchildren are a subject of concern due to their prevalence and potential health impact. Understanding and addressing this issue is crucial for public health in the region. We conducted a comprehensive search for articles published up to December 2023 across four databases, including Scopus, PubMed, ProQuest, and Web of Science. To estimate the combined prevalence, a random-effects model with a 95% confidence interval (CI) was applied, and the statistical analysis was performed using meta-analysis packages in R version (3.6.1). This study is registered with PROSPERO (CRD42023481146). Among 131 eligible articles, the prevalence of intestinal protozoan parasites was 0.208 (95% CI = 0.180-0.238). Lebanon and Tajikistan had the highest country-level prevalence at 0.851 and 0.836, respectively, with Giardia duodenalis being the most prevalent species at 0.082. In summary, our study highlights the urgent public health issue of protozoan parasites among Asian schoolchildren due to poor sanitation and water quality. Immediate interventions are essential, considering climate and socioeconomic factors, to combat these infections and improve overall health.

Identifiants

pubmed: 38982017
doi: 10.1007/s15010-024-02339-1
pii: 10.1007/s15010-024-02339-1
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Qazvin University of Medical Sciences
ID : IR.QUMS.REC.1402.150

Informations de copyright

© 2024. The Author(s).

Références

Fletcher SM, Stark D, Harkness J, Ellis J. Enteric protozoa in the developed world: a public health perspective. Clin Microbiol Rev. 2012;25:420–49.
doi: 10.1128/CMR.05038-11 pubmed: 22763633 pmcid: 3416492
Eslahi AV, Olfatifar M, Zaki L, Pirestani M, Sotoodeh S, Farahvash MA, et al. The worldwide prevalence of intestinal helminthic parasites among food handlers: a systematic review and meta-analysis. Food Control. 2023;2: 109658.
doi: 10.1016/j.foodcont.2023.109658
WHO. Soil-transmitted helminth infections. WHO Fact Sheets. World Health Organization Geneva, Switzerland; 2020.
Siddig HS, Mohammed IA, Mohammed MN, Bashir AM. Prevalence of intestinal parasites among selected group of primary school children in Alhag Yousif Area, Khartoum, Sudan. Int J Med Res Heal Sci. 2017;6:125–31.
Gupta R, Rayamajhee B, Sherchan SP, Rai G, Mukhiya RK, Khanal B, et al. Prevalence of intestinal parasitosis and associated risk factors among school children of Saptari district, Nepal: a cross-sectional study. Trop Med Health. 2020;48:1–9.
doi: 10.1186/s41182-020-00261-4
Eslahi AV, Olfatifar M, Zaki L, Saryazdi AK, Barikbin F, Maleki A, et al. Global prevalence of intestinal protozoan parasites among food handlers: A systematic review and meta-analysis. Food Control. 2022;2: 109466.
Huh S, Yu J-R, Kim J-I, Gotov C, Janchiv R, Seo J-S. Intestinal protozoan infections and echinococcosis in the inhabitants of Dornod and Selenge, Mongolia (2003). Korean J Parasitol. 2006;44:171.
doi: 10.3347/kjp.2006.44.2.171 pubmed: 16809968 pmcid: 2532637
Sutrave S, Richter MH. The Truman Show for protozoan parasites: a review of in vitro cultivation platforms. PLoS Negl Trop Dis. 2021;15: e0009668.
doi: 10.1371/journal.pntd.0009668 pubmed: 34437538 pmcid: 8389406
Hemphill A, Müller N, Müller J. Comparative pathobiology of the intestinal protozoan parasites Giardia lamblia, Entamoeba histolytica, and Cryptosporidium parvum. Pathogens. 2019;8:116.
doi: 10.3390/pathogens8030116 pubmed: 31362451 pmcid: 6789772
Ahmed T, Khanum H, Uddin MS, Barua P, Arju T, Kabir M, et al. Entamoeba histolytica, Giardia lamblia and Cryptosporidium spp. infection in children in an urban slum area of Bangladesh. Bioresearch Commun. 2016;2:175–81.
Eckmann L, Gillin FD. Microbes and microbial toxins: paradigms for microbial-mucosal interactions I. Pathophysiological aspects of enteric infections with the lumen-dwelling protozoan pathogen Giardia lamblia. Am J Physiol Liver Physiol. 2001;280:1–6.
Moges F, Belyhun Y, Tiruneh M, Kebede Y, Mulu A, Kassu A, et al. Comparison of formol-acetone concentration method with that of the direct iodine preparation and formol-ether concentration methods for examination of stool parasites. Ethiop J Heal Dev. 2010;24:2.
Venturini E, Scarso S, Prelazzi GA, Niccolai C, Bianchi L, Montagnani C, et al. Epidemiology and clinical features of intestinal protozoan infections detected by Real-time PCR in non-native children within an Italian tertiary care children’s hospital: a cross-sectional study. Travel Med Infect Dis. 2021;43: 102107.
doi: 10.1016/j.tmaid.2021.102107 pubmed: 34116243
Selçuk AA. A guide for systematic reviews: PRISMA. Turkish Arch Otorhinolaryngol. 2019;57:57.
doi: 10.5152/tao.2019.4058
Abdoli A, Olfatifar M, Eslahi AV, Moghadamizad Z, Samimi R, Habibi MA, et al. A systematic review and meta-analysis of protozoan parasite infections among patients with mental health disorders: an overlooked phenomenon. Gut Pathog. 2024;16:7.
doi: 10.1186/s13099-024-00602-2 pubmed: 38282036 pmcid: 10822187
Barendregt JJ, Doi SA. MetaXL user guide Version. 2016;4:2011–6.
Team RC. R Core Team R. R: A Language and Environment for Statistical Computing R Foundation for Statistical Computing, Vienna, Austria; 2016. ISBN 3–900051–07–0
Elmonir W, Elaadli H, Amer A, El-Sharkawy H, Bessat M, Mahmoud SF, et al. Prevalence of intestinal parasitic infections and their associated risk factors among preschool and school children in Egypt. PLoS ONE. 2021;16: e0258037.
doi: 10.1371/journal.pone.0258037 pubmed: 34587187 pmcid: 8480785
Bourli P, Eslahi AV, Tzoraki O, Karanis P. Waterborne transmission of protozoan parasites: a review of worldwide outbreaks–an update 2017–2022. J Water Health. 2023;21:1421–47.
doi: 10.2166/wh.2023.094 pubmed: 37902200
EFSA Panel on Biological Hazards (BIOHAZ), Koutsoumanis K, Allende A, Alvarez-Ordóñez A, Bolton D, Bover-Cid S, et al. Public health risks associated with food-borne parasites. EFSA J. 2018;16:e05495.
Omarova A, Tussupova K, Berndtsson R, Kalishev M, Sharapatova K. Protozoan parasites in drinking water: A system approach for improved water, sanitation and hygiene in developing countries. Int J Environ Res Public Health. 2018;15:495.
doi: 10.3390/ijerph15030495 pubmed: 29534511 pmcid: 5877040
Kalavani S, Matin S, Rahmanian V, Meshkin A, Taghipour A, Abdoli A. Prevalence of Giardia duodenalis among Asian children: a systematic review and meta-analysis. Int Health. 2023;2:37.
Heresi GP, Murphy JR, Cleary TG. Giardiasis. Semin Pediatr Infect Dis. 2000. p. 189–95.
Dixon BR. Giardia duodenalis in humans and animals-Transmission and disease. Res Vet Sci. 2021;135:283–9.
doi: 10.1016/j.rvsc.2020.09.034 pubmed: 33066992
Hunter PR, Thompson RCA. The zoonotic transmission of Giardia and Cryptosporidium. Int J Parasitol. 2005;35:1181–90.
doi: 10.1016/j.ijpara.2005.07.009 pubmed: 16159658
Siwila J. The Triple Food-borne Protozoan Parasites: Cryptosporidium spp, Giardia duodenalis, Cyclospora cayetanensis Hope in Transmission Reduction. Curr Clin Microbiol Rep. 2023;2:1–9.
Maikai BV, Umoh JU, Lawal IA, Kudi AC, Ejembi CL, Xiao LH. Molecular characterizations of Cryptosporidium, Giardia, and Enterocytozoon in humans in Kaduna State. Nigeria Exp Parasitol. 2012;131:452–6.
doi: 10.1016/j.exppara.2012.05.011 pubmed: 22664352
El Safadi D, Osman M, Hanna A, Hajar I, Kassem II, Khalife S, et al. Parasitic Contamination of Fresh Leafy Green Vegetables Sold in Northern Lebanon. Pathogens. MDPI; 2023. p. 1014.
Matthys B, Bobieva M, Karimova G, Mengliboeva Z, Jean-Richard V, Hoimnazarova M, et al. Prevalence and risk factors of helminths and intestinal protozoa infections among children from primary schools in western Tajikistan. Parasit Vectors. 2011;4:1–13.
doi: 10.1186/1756-3305-4-195
United Nations Development Programme Tajikistan R of T. Progress toward the Millennium Development Goals (Tajikistan 2003). United Nations Development Programme Dushanbe, Tajikistan; 2003.
Steinmann P, Usubalieva J, Imanalieva C, Minbaeva G, Stefiuk K, Jeandron A, et al. Rapid appraisal of human intestinal helminth infections among schoolchildren in Osh oblast. Kyrgyzstan Acta Trop. 2010;116:178–84.
doi: 10.1016/j.actatropica.2010.06.008 pubmed: 20615381
Bekturganov Z, Tussupova K, Berndtsson R, Sharapatova N, Aryngazin K, Zhanasova M. Water related health problems in Central Asia A review. Water. 2016;8:219.
doi: 10.3390/w8060219
Kuete T, Yemeli FLS, Mvoa EE, Nkoa T, Somo RM, Ekobo AS. Prevalence and risk factors of intestinal helminth and protozoa infections in an urban setting of Cameroon: the case of Douala. Am J Epidemiol Infect Dis. 2015;3:36–44.
Hajare ST, Chekol Y, Chauhan NM. Assessment of prevalence of Giardia lamblia infection and its associated factors among government elementary school children from Sidama zone, SNNPR. Ethiopia PLoS One. 2022;17: e0264812.
doi: 10.1371/journal.pone.0264812 pubmed: 35290402
Ndeezi G, Mor SM, Ascolillo LR, Tasimwa HB, Nakato R, Kayondo LN, et al. Giardia duodenalis in Ugandan Children Aged 9–36 Months in Kampala, Uganda: Prevalence and Associated Factors. Am J Trop Med Hyg. 2023;109:147.
doi: 10.4269/ajtmh.22-0436 pubmed: 37253438 pmcid: 10324004
Hotez PJ, Bottazzi ME, Strych U, Chang L-Y, Lim YAL, Goodenow MM, et al. Neglected tropical diseases among the Association of Southeast Asian Nations (ASEAN): overview and update. PLoS Negl Trop Dis. 2015;9: e0003575.
doi: 10.1371/journal.pntd.0003575 pubmed: 25880767 pmcid: 4400050
Fuhrimann S. Health risk assessment along wastewater recovery and reuse systems in Kampala, Uganda and Hanoi. Vietnam: University of Basel; 2015.
Antoszczak Michałand Steverding D, Huczyński A. Anti-parasitic activity of polyether ionophores. Eur J Med Chem. 2019;166:32–47.
Tidman R, Abela-Ridder B, de Castañeda RR. The impact of climate change on neglected tropical diseases: a systematic review. Trans R Soc Trop Med Hyg. 2021;115:147–68.
doi: 10.1093/trstmh/traa192 pubmed: 33508094 pmcid: 7842100
Ahmed A, Al-Mekhlafi HM, Choy SH, Ithoi I, Al-Adhroey AH, Abdulsalam AM, et al. The burden of moderate-to-heavy soil-transmitted helminth infections among rural malaysian aborigines: an urgent need for an integrated control programme. Parasit Vectors. 2011;4:1–7.
doi: 10.1186/1756-3305-4-242
Eyamo T, Girma M, Alemayehu T, Bedewi Z. Soil-transmitted helminths and other intestinal parasites among schoolchildren in Southern Ethiopia. Res Rep Trop Med. 2019;137–43.
Guy RA, Xiao C, Horgen PA. Real-time PCR assay for detection and genotype differentiation of Giardia lamblia in stool specimens. J Clin Microbiol. 2004;42:3317–20.
doi: 10.1128/JCM.42.7.3317-3320.2004 pubmed: 15243104 pmcid: 446313
Hamad I, Raoult D, Bittar F. Repertory of eukaryotes (eukaryome) in the human gastrointestinal tract: taxonomy and detection methods. Parasite Immunol. 2016;38:12–36.
doi: 10.1111/pim.12284 pubmed: 26434599

Auteurs

Amir Abdoli (A)

Zoonoses Research Center, Jahrom University of Medical Sciences, Jahrom, Iran.
Department of Parasitology and Mycology, Jahrom University of Medical Sciences, Jahrom, Iran.

Meysam Olfatifar (M)

Gastroenterology and Hepatology Diseases Research Center, Qom University of Medical Sciences, Qom, Iran.

Aida Vafae Eslahi (AV)

Medical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.

Zeinab Moghadamizad (Z)

Department of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.

Oskar Nowak (O)

Institute of Human Biology and Evolution, Faculty of Biology, Adam Mickiewicz University, Poznań, Poland.

Majid Pirestani (M)

Department of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.

Amir Karimipour-Saryazdi (A)

Department of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.

Milad Badri (M)

Medical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran. badri22.milad@gmail.com.

Panagiotis Karanis (P)

Medical Faculty and University Hospital, University of Cologne, Cologne, Germany. karanis.p@unic.ac.cy.
Department of Basic and Clinical Sciences, Medical School, Anatomy Centre, University of Nicosia, Nicosia, Cyprus. karanis.p@unic.ac.cy.

Classifications MeSH