Pilomatrixoma of the Periorbital Region: A Retrospective Review.
Journal
Ophthalmic plastic and reconstructive surgery
ISSN: 1537-2677
Titre abrégé: Ophthalmic Plast Reconstr Surg
Pays: United States
ID NLM: 8508431
Informations de publication
Date de publication:
10 Jul 2024
10 Jul 2024
Historique:
medline:
10
7
2024
pubmed:
10
7
2024
entrez:
10
7
2024
Statut:
aheadofprint
Résumé
Pilomatrixoma is a benign cutaneous adnexal tumor that differentiates toward hair follicle cells. It infrequently occurs in the periorbital region. In the periorbital area, it is often located in the upper eyelid and eyebrow region. Periorbital pilomatrixoma is often misdiagnosed clinically and is less common than other benign skin tumors. In this retrospective review, we evaluate the demographic, clinical, and histopathological data of patients with periorbital pilomatrixoma, treated from 2010 to 2023. A retrospective analysis of periorbital pilomatrixoma cases treated during a period of 13 years was performed. Deidentified data in relation to the age at surgical excision, gender, location, size, histopathological features, treatment, and recurrence were collected. All histological slides were reviewed by an attending histopathologist. A total of 77 cases of periorbital pilomatrixoma were diagnosed by histopathological examination and treated from 2010 to 2023. A slight female preponderance (56%) was noted, and the majority of cases (52%) were presented in the first 2 decades of life. The left periorbital region was involved in 45.5% of cases, and 54.5% in the right. The upper lid was the most affected site. Two cases of recurrence were reported. No malignant transformation was noted. Pilomatrixoma is an uncommon benign periorbital tumor, commonly misdiagnosed clinically. Ophthalmologists and surgeons should suspect pilomatrixoma in the periorbital region, especially in children or young adults. Complete surgical excision is curative, and recurrence is rare.
Identifiants
pubmed: 38984650
doi: 10.1097/IOP.0000000000002731
pii: 00002341-990000000-00422
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2024 The American Society of Ophthalmic Plastic and Reconstructive Surgery, Inc.
Déclaration de conflit d'intérêts
The authors have no financial or conflicts of interest to disclose.
Références
Duflo S, Nicollas R, Roman S, et al. Pilomatrixoma of the head and neck in children: a study of 38 cases and a review of the literature. Arch Otolaryngol Head Neck Surg 1998;124:1239–1242.
Forbis R Jr., Helwig EB. Pilomatrixoma (calcifying epithelioma). Arch Dermatol 1961;83:606–618.
Boniuk M, Zimmerman LE. Pilomatrixoma (benign calcifying epithelioma) of the eyelids and eyebrow. Arch Ophthalmol 1963;70:399–406.
Perez RC, Nicholson DH. Malherbe’s calcifying epithelioma (pilomatrixoma) of the eyelid. clinical features. Arch Ophthalmol 1979;97:314–315.
Pirouzmanesh A, Reinisch JF, Gonzalez-Gomez I, et al. Pilomatrixoma: a review of 346 cases. Plast Reconstr Surg 2003;112:1784–1789.
Lan MY, Lan MC, Ho CY, et al. Pilomatricoma of the head and neck: a retrospective review of 179 cases. Arch Otolaryngol Head Neck Surg 2003;129:1327–1330.
Kumaran N, Azmy A, Carachi R, et al. Pilomatrixoma--accuracy of clinical diagnosis. J Pediatr Surg 2006;41:1755–1758.
Le C, Bedocs PM. Calcifying Epithelioma of Malherbe. StatPearls Publishing LLC.; 2023.
Jones CD, Ho W, Robertson BF, et al. Pilomatrixoma: a comprehensive review of the literature. Am J Dermatopathol 2018;40:631–641.
Zloto O, Fabian ID, Dai VV, et al. Periocular pilomatrixoma: a retrospective analysis of 16 cases. Ophthalmic Plast Reconstr Surg 2015;31:19–22.
Hernández-Núñez A, Nájera Botello L, Romero Maté A, et al. Retrospective study of pilomatricoma: 261 tumors in 239 patients. Actas Dermosifiliogr 2014;105:699–705.
Julian CG, Bowers PW. A clinical review of 209 pilomatricomas. J Am Acad Dermatol 1998;39:191–195.
Agarwal RP, Handler SD, Matthews MR, et al. Pilomatrixoma of the head and neck in children. Otolaryngol Head Neck Surg 2001;125:510–515.
Levy J, Ilsar M, Deckel Y, et al. Eyelid pilomatrixoma: a description of 16 cases and a review of the literature. Surv Ophthalmol 2008;53:526–535.
Arif T, Amin SS, Raj D. Pilomatricoma of the eyelid. Our Dermatol Online 2018;9:73–74.
Kaddu S, Soyer HP, Cerroni L, et al. Clinical and histopathologic spectrum of pilomatricomas in adults. Int J Dermatol 1994;33:705–708.
Gündüz K, Ecel M, Erden E. Multiple pilomatrixomas affecting the eyelid and face. J Pediatr Ophthalmol Strabismus 2008;45:122–124.
Guinot-Moya R, Valmaseda-Castellon E, Berini-Aytes L, et al. Pilomatrixoma. Review of 205 cases. Med Oral Patol Oral Cir Bucal 2011;16:e552–e555.
Schwarz Y, Pitaro J, Waissbluth S, et al. Review of pediatric head and neck pilomatrixoma. Int J Pediatr Otorhinolaryngol 2016;85:148–153.
Siadati S, Campbell AA, McCulley T, et al. Clinicopathological features of 19 eyelid pilomatrixomas. Ocul Oncol Pathol 2022;8:30–34.
Prateek J, Sapna B, Anshuman P, et al. A case report of eyelid pilomatrixoma: a rare presentation. Kerala J Ophthalmol 2022;34:268–270.
Mathen LC, Olver JM, Cree IA. A large rapidly growing pilomatrixoma on a lower eyelid. Br J Ophthalmol 2000;84:1203–1204.
Abalo-Lojo JM, Cameselle-Teijeiro J, Gonzalez F. Pilomatrixoma: late onset in two periocular cases. Ophthalmic Plast Reconstr Surg 2008;24:60–62.
Herwig MC, Vogel A, Holz FG, et al. [Pilomatrixoma of the ocular adnexae: clinical and histologic analysis (13 cases)]. Klin Monbl Augenheilkd 2009;226:404–408.
Chan JJ, Tey HL. Multiple pilomatricomas: case presentation and review of the literature. Dermatol Online J 2010;16:2.
Veena KM, Chandra J. Pilomatrixoma: a common tumour of head and neck, but rarely reported. BMJ Case Rep 2021;14:e238033.
Ciriacks K, Knabel D, Waite MB. Syndromes associated with multiple pilomatricomas: when should clinicians be concerned? Pediatr Dermatol 2020;37:9–17.
Mesa-Álvarez L, Batalla A, Iglesias-Puzas A, et al. Multiple pilomatricomas: a retrospective study and literature review. Am J Dermatopathol 2019;41:293–295.
Kwon D, Grekov K, Krishnan M, et al. Characteristics of pilomatrixoma in children: a review of 137 patients. Int J Pediatr Otorhinolaryngol 2014;78:1337–1341.
Kumar S. Rapidly growing pilomatrixoma on eyebrow. Indian J Ophthalmol 2008;56:83–84.
Han G, Kim AR, Song HJ, et al. Updated view on epidemiology and clinical aspects of pilomatricoma in adults. Int J Dermatol 2017;56:1032–1036.
Izquierdo-Rodríguez C, Mencía-Gutiérrez E, Gutiérrez-Díaz E, et al. [An unusual presentation of a pilomatrixoma in the eyelid]. Arch Soc Esp Oftalmol 2006;81:483–486.
Ni C, Kimball GP, Craft JL, et al. Calcifying epithelioma: a clinicopathological analysis of 67 cases with ultrastructural study of 2 cases. Int Ophthalmol Clin 1982;22:63–86.
Schaefer I-M, Gronchi A. WHO pathology. Surg Oncol Clin N Am 2022;31:321–340.
Dittrich MR, De Sousa JM, Manso PG. Atypical presentation of pilomatrixoma in the tarsal conjunctiva. Revista Brasileira de Oftalmologia 2016;75:238–240.
Rizvi SA, Naim M, Alam MS. A giant upper eyelid ossifying pilomatrixoma. Indian J Ophthalmol 2008;56:509–511.
Cornejo KM, Deng A. Pilomatrix carcinoma: a case report and review of the literature. Am J Dermatopathol 2013;35:389–394.