CryoET of β-amyloid and tau within postmortem Alzheimer's disease brain.


Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
10 Jul 2024
Historique:
received: 24 06 2023
accepted: 06 06 2024
medline: 11 7 2024
pubmed: 11 7 2024
entrez: 10 7 2024
Statut: aheadofprint

Résumé

A defining pathological feature of most neurodegenerative diseases is the assembly of proteins into amyloid that form disease-specific structures

Identifiants

pubmed: 38987603
doi: 10.1038/s41586-024-07680-x
pii: 10.1038/s41586-024-07680-x
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s).

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Auteurs

Madeleine A G Gilbert (MAG)

Astbury Centre for Structural Molecular Biology, School of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, Leeds, UK.

Nayab Fatima (N)

Astbury Centre for Structural Molecular Biology, School of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, Leeds, UK.

Joshua Jenkins (J)

Astbury Centre for Structural Molecular Biology, School of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, Leeds, UK.

Thomas J O'Sullivan (TJ)

Astbury Biostructure Laboratory CryoEM facility, Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK.

Andreas Schertel (A)

ZEISS Microscopy Customer Center Europe, Carl Zeiss Microscopy GmbH, Oberkochen, Germany.

Yehuda Halfon (Y)

Astbury Biostructure Laboratory CryoEM facility, Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK.

Martin Wilkinson (M)

Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK.

Tjado H J Morrema (THJ)

Department of Pathology, Unit Neuropathology, Amsterdam University Medical Centers, Amsterdam, The Netherlands.

Mirjam Geibel (M)

ZEISS Microscopy Customer Center Europe, Carl Zeiss Microscopy GmbH, Oberkochen, Germany.

Randy J Read (RJ)

Department of Haematology, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.

Neil A Ranson (NA)

Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK.

Sheena E Radford (SE)

Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK.

Jeroen J M Hoozemans (JJM)

Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK.

René A W Frank (RAW)

Astbury Centre for Structural Molecular Biology, School of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, Leeds, UK. r.frank@leeds.ac.uk.

Classifications MeSH