Virus-Shaped Mesoporous Silica Nanostars to Improve the Transport of Drugs across the Blood-Brain Barrier.

blood–brain barrier model brain diseases mesoporous silica nanoparticle molecular dynamics simulation nanostar

Journal

ACS applied materials & interfaces
ISSN: 1944-8252
Titre abrégé: ACS Appl Mater Interfaces
Pays: United States
ID NLM: 101504991

Informations de publication

Date de publication:
10 Jul 2024
Historique:
medline: 11 7 2024
pubmed: 11 7 2024
entrez: 11 7 2024
Statut: aheadofprint

Résumé

Conditions affecting the brain are the second leading cause of death globally. One of the main challenges for drugs targeting brain diseases is passing the blood-brain barrier (BBB). Here, the effectiveness of mesoporous silica nanostars (MSiNSs) with two different spike lengths to cross an

Identifiants

DOI: 10.1021/acsami.4c06726 PMID: 38988046
pubmed: 38988046
doi: 10.1021/acsami.4c06726
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Alessandra Pinna (A)

School of Veterinary Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, U.K.
The Francis Crick Institute, NW1 1AT London, U.K.
Department of Materials, Imperial College London, SW7 2AZ London, U.K.
ORCID: 0009-0001-4467-8484

Ieva Ragaisyte (I)

Department of Materials, Imperial College London, SW7 2AZ London, U.K.

William Morton (W)

Department of Materials, Imperial College London, SW7 2AZ London, U.K.
ORCID: 0000-0002-2584-8548

Stefano Angioletti-Uberti (S)

Department of Materials, Imperial College London, SW7 2AZ London, U.K.

Alizé Proust (A)

The Francis Crick Institute, NW1 1AT London, U.K.

Rocco D'Antuono (R)

Crick Advanced Light Microscopy STP, The Francis Crick Institute, NW1 1AT London, U.K.
Department of Biomedical Engineering, School of Biological Sciences, University of Reading, Reading RG6 6AY, U.K.

Chak Hon Luk (CH)

The Francis Crick Institute, NW1 1AT London, U.K.

Maximiliano G Gutierrez (MG)

The Francis Crick Institute, NW1 1AT London, U.K.
ORCID: 0000-0003-3199-0337

Maddalena Cerrone (M)

The Francis Crick Institute, NW1 1AT London, U.K.

Katalin A Wilkinson (KA)

The Francis Crick Institute, NW1 1AT London, U.K.
Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory, Cape Town 7925, Republic of South Africa.
Department of Medicine, University of Cape Town, Observatory, Cape Town 7925, Republic of South Africa.

Ali A Mohammed (AA)

Dyson School of Design Engineering, Imperial College London, SW7 2AZ London, U.K.
School of Design, Royal College of Art, SW11 4AY London, U.K.

Catriona M McGilvery (CM)

Department of Materials, Imperial College London, SW7 2AZ London, U.K.
ORCID: 0000-0002-4849-0251

Alejandro Suárez-Bonnet (A)

The Francis Crick Institute, NW1 1AT London, U.K.
Department of Pathobiology and Population Sciences, The Royal Veterinary College, North Mimms, Hatfield, Hertfordshire AL9 7TA, U.K.

Matthew Zimmerman (M)

Center for Discovery and Innovation, Hackensack Meridian Health, 111 Ideation Way, Nutley, New Jersey 07110, United States.

Martin Gengenbacher (M)

Center for Discovery and Innovation, Hackensack Meridian Health, 111 Ideation Way, Nutley, New Jersey 07110, United States.
Hackensack Meridian School of Medicine, Nutley, New Jersey 07110, United States.
ORCID: 0000-0002-0208-5920

Robert J Wilkinson (RJ)

The Francis Crick Institute, NW1 1AT London, U.K.
Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory, Cape Town 7925, Republic of South Africa.
Department of Medicine, University of Cape Town, Observatory, Cape Town 7925, Republic of South Africa.
Department of Infectious Diseases, Imperial College London, W12 0NN London, U.K.

Alexandra E Porter (AE)

Department of Materials, Imperial College London, SW7 2AZ London, U.K.

Classifications MeSH