Multikingdom oral microbiome interactions in early-onset cryptogenic ischemic stroke.

biomarkers cerebrovascular disorders co-abundance analysis cryptogenic ischemic stroke metagenomics multikingdom oral microbiome saliva stroke

Journal

ISME communications
ISSN: 2730-6151
Titre abrégé: ISME Commun
Pays: England
ID NLM: 9918205372406676

Informations de publication

Date de publication:
Jan 2024
Historique:
received: 27 12 2023
revised: 15 04 2024
accepted: 19 06 2024
medline: 11 7 2024
pubmed: 11 7 2024
entrez: 11 7 2024
Statut: epublish

Résumé

Although knowledge of the role of the oral microbiome in ischemic stroke is steadily increasing, little is known about the multikingdom microbiota interactions and their consequences. We enrolled participants from a prospective multicentre case-control study and investigated multikingdom microbiome differences using saliva metagenomic datasets (

Identifiants

pubmed: 38988699
doi: 10.1093/ismeco/ycae088
pii: ycae088
pmc: PMC11235082
doi:

Types de publication

Journal Article

Langues

eng

Pagination

ycae088

Informations de copyright

© The Author(s) 2024. Published by Oxford University Press on behalf of the International Society for Microbial Ecology.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

Auteurs

Muhammed Manzoor (M)

Department of Oral and Maxillofacial Diseases, University of Helsinki, 00014 Helsinki, Finland.

Jaakko Leskelä (J)

Department of Oral and Maxillofacial Diseases, University of Helsinki, 00014 Helsinki, Finland.

Milla Pietiäinen (M)

Department of Oral and Maxillofacial Diseases, University of Helsinki, 00014 Helsinki, Finland.
Industrial Biotechnology and Food Protein Production, VTT Technical Research Centre of Finland, 02044 Espoo, Finland.

Nicolas Martinez-Majander (N)

Department of Neurology, Helsinki University Hospital and University of Helsinki, 00290 Helsinki, Finland.

Pauli Ylikotila (P)

Neurocenter, Turku University Hospital, University of Turku, 20521 Turku, Finland.

Eija Könönen (E)

Institute of Dentistry, University of Turku, 20500 Turku, Finland.

Teemu Niiranen (T)

Department of Public Health and Welfare, Finnish Institute for Health and Welfare, 00271 Helsinki, Finland.
Department of Internal Medicine, Turku University Hospital and University of Turku, 20521 Turku, Finland.

Leo Lahti (L)

Department of Computing, University of Turku, 20500 Turku, Finland.

Juha Sinisalo (J)

Heart and Lung Center, Helsinki University Central Hospital, and Helsinki University, 00260 Helsinki, Finland.

Jukka Putaala (J)

Department of Neurology, Helsinki University Hospital and University of Helsinki, 00290 Helsinki, Finland.

Pirkko J Pussinen (PJ)

Department of Oral and Maxillofacial Diseases, University of Helsinki, 00014 Helsinki, Finland.
School of Medicine, Institute of Dentistry, University of Eastern Finland, 70211 Kuopio, Finland.

Susanna Paju (S)

Department of Oral and Maxillofacial Diseases, University of Helsinki, 00014 Helsinki, Finland.

Classifications MeSH