Matrix metalloproteinase inhibitors in restorative dentistry.
Matrix metalloproteinase inhibitors and bond strength
matrix metalloproteinase inhibitors
matrix metalloproteinases
Journal
Journal of conservative dentistry and endodontics
ISSN: 2950-4708
Titre abrégé: J Conserv Dent Endod
Pays: India
ID NLM: 9918697474706676
Informations de publication
Date de publication:
Jun 2024
Jun 2024
Historique:
received:
11
04
2024
revised:
24
04
2024
accepted:
25
04
2024
medline:
11
7
2024
pubmed:
11
7
2024
entrez:
11
7
2024
Statut:
ppublish
Résumé
Matrix metalloproteinases (MMPs) have been identified as agents that disintegrate the collagen structures of dental hybrid layers, resulting in reduced restorative bond strength. Multiple MMP inhibitors (MMPIs) are known to counteract this degenerative mechanism, thereby preserving bond strength and promoting the longevity of resin-based restorations. Additionally, literature suggests that certain MMPI materials possess antimicrobial/anticariogenic properties, potentially reducing the risk of secondary caries development. Therefore, this review article aims to narrate on the integration of matrix metalloproteinase inhibitors into adhesive systems and their impact on bond strength.
Identifiants
pubmed: 38989495
doi: 10.4103/JCDE.JCDE_199_24
pii: JCDE-27-566
pmc: PMC11232771
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
566-571Informations de copyright
Copyright: © 2024 Journal of Conservative Dentistry and Endodontics.
Déclaration de conflit d'intérêts
There are no conflicts of interest.