Pancreas transplantation with grafts obtained from donation after cardiac death or donation after brain death results in comparable outcomes.
delayed graft function (DGF)
donation after brain death (DBD)
donation after cardiac death (DCD)
pancreas after kidney transplant (PAK)
pancreas transplant alone (PTA)
pancreas transplantation
simultaneous kidney and pancreas transplant (SPK)
Journal
Frontiers in transplantation
ISSN: 2813-2440
Titre abrégé: Front Transplant
Pays: Switzerland
ID NLM: 9918573988006676
Informations de publication
Date de publication:
2023
2023
Historique:
received:
28
02
2023
accepted:
21
07
2023
medline:
12
7
2024
pubmed:
12
7
2024
entrez:
12
7
2024
Statut:
epublish
Résumé
Pancreas organ shortages and long recipient waitlist times are critical components that limit recipients from receiving a pancreas transplant. Over the last decade, our center has been using donation after cardiac death (DCD) donors as an adjunct to donation after brain death (DBD) donors to expand the organ pool. The aim of this study was to compare recipient and graft survival between DCD and DBD recipients. A retrospective single center propensity matched analysis (2011-2020) of 32 DCD vs 96 DBD pancreas transplants was performed. 8-year recipient survival was similar between DCD and DBD groups (87.4% vs 92.7%, Recipients of DCD grafts demonstrate equivalent long-term patient and graft survival compared to DBD recipients for pancreas transplantation. Increased utilization of well selected DCD donors is a safe strategy to increase the donor pool.
Identifiants
pubmed: 38993888
doi: 10.3389/frtra.2023.1176398
pmc: PMC11235253
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1176398Informations de copyright
© 2023 Bleszynski, Parmentier, Torres-Hernandez, Ray, Yousuf, Norgate, Schiff, Shwaartz, Sapisochin, McGilvray, Selzner and Reichman.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.