Role of elective neck dissection in cT2N0 maxillary sinus squamous cell carcinoma.
Elective neck dissection
Maxillary sinus squamous cell carcinoma
Occult metastasis
PSM
Survival
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
14 Jul 2024
14 Jul 2024
Historique:
received:
23
01
2024
accepted:
27
06
2024
medline:
15
7
2024
pubmed:
15
7
2024
entrez:
14
7
2024
Statut:
epublish
Résumé
Our objective was to examine the impact of elective neck dissection (END) on the prognosis of patients with cT2N0 maxillary sinus squamous cell carcinoma (MS-SCC) and to determine factors that predict the occurrence of occult metastasis in this patient population. A retrospective analysis was conducted using data from the SEER database. Patients with cT2N0 MS-SCC were included in the study and divided into two groups: those who received END and those who did not. The impact of END on disease-specific survival (DSS) and overall survival (OS) was assessed using propensity score matching. Multivariate logistic regression analysis was performed to determine predictors for occult metastasis. A total of 180 patients were included in the study, with 40 cases receiving END. Following propensity score matching, patients treated with END and those without showed similar DSS and OS rates. Occult metastasis was observed in 9 patients, corresponding to a rate of 22.5%. High-grade tumors were independently associated with a higher risk of occult metastasis compared to low-grade tumors (hazard ratio 1.52, 95% confidence interval 1.17-2.00). cT2 MS-SCC carries an occult metastasis rate of 22.5%, with histologic grade being the primary determinant of occult metastasis. END does not confer a significant survival benefit in this patient population.
Identifiants
pubmed: 39004629
doi: 10.1038/s41598-024-66179-7
pii: 10.1038/s41598-024-66179-7
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
16230Subventions
Organisme : Henan provincial Medical Science and Technology Research Project
ID : LHGJ20220196
Organisme : Project of Science and Technology in Science and Technology Department of Henan Province
ID : 232102310285
Informations de copyright
© 2024. The Author(s).
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