The prevalence of vertical transmission of human immunodeficiency virus and associated factors among exposed infants in Eastern Lake zone and Southern Highland of Tanzania: a cross-sectional study.
Humans
Infectious Disease Transmission, Vertical
/ statistics & numerical data
Tanzania
/ epidemiology
HIV Infections
/ transmission
Cross-Sectional Studies
Female
Prevalence
Retrospective Studies
Infant
Adult
Pregnancy
Male
Infant, Newborn
Pregnancy Complications, Infectious
/ epidemiology
Young Adult
Risk Factors
HIV-exposed infants
Prevalence
vertical transmission
Journal
HIV research & clinical practice
ISSN: 2578-7470
Titre abrégé: HIV Res Clin Pract
Pays: England
ID NLM: 101738312
Informations de publication
Date de publication:
Dec 2024
Dec 2024
Historique:
medline:
16
7
2024
pubmed:
16
7
2024
entrez:
16
7
2024
Statut:
ppublish
Résumé
Globally, the rate of antiretroviral therapy coverage for pregnant women living with human immunodeficiency virus (HIV) increased by 38% between 2010 and 2015 but only by 2% between 2016 and 2020. We aimed to determine the prevalence of vertical transmission of HIV among infants from mothers living with HIV and associated factors in the Eastern Lake Zone and Southern Highland of Tanzania from January to December 2022. This retrospective cross-sectional study extracted data from the Open Laboratory Data Repository database collected from January to December 2022 at 93 health facilities. A total of 1,411 infants exposed to HIV from the Mbeya (851), Songwe (304), and Mara regions (256) were enrolled. The prevalence for vertical transmission of HIV was 2.48% (35/1411). We observed a non-significant difference in the prevalence of vertical transmission in children whose first test was done below six weeks of life (1.89%) and other age groups (2.52-2.62%) ( We found a low prevalence of vertical transmission of HIV compared to previous studies done in Tanzania. The use of ART prophylaxis for infants exposed to HIV is significantly associated with the low rate of HIV transmission.
Sections du résumé
BACKGROUND
UNASSIGNED
Globally, the rate of antiretroviral therapy coverage for pregnant women living with human immunodeficiency virus (HIV) increased by 38% between 2010 and 2015 but only by 2% between 2016 and 2020.
OBJECTIVES
UNASSIGNED
We aimed to determine the prevalence of vertical transmission of HIV among infants from mothers living with HIV and associated factors in the Eastern Lake Zone and Southern Highland of Tanzania from January to December 2022.
METHODS
UNASSIGNED
This retrospective cross-sectional study extracted data from the Open Laboratory Data Repository database collected from January to December 2022 at 93 health facilities. A total of 1,411 infants exposed to HIV from the Mbeya (851), Songwe (304), and Mara regions (256) were enrolled.
RESULTS
UNASSIGNED
The prevalence for vertical transmission of HIV was 2.48% (35/1411). We observed a non-significant difference in the prevalence of vertical transmission in children whose first test was done below six weeks of life (1.89%) and other age groups (2.52-2.62%) (
CONCLUSIONS
UNASSIGNED
We found a low prevalence of vertical transmission of HIV compared to previous studies done in Tanzania. The use of ART prophylaxis for infants exposed to HIV is significantly associated with the low rate of HIV transmission.
Identifiants
pubmed: 39012073
doi: 10.1080/25787489.2024.2378575
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM