Sex-related variability of white matter tracts in the whole HCP cohort.
Diffusion Magnetic Resonance Imaging
Microstructure
Sex differences
Tractography
White matter
Journal
Brain structure & function
ISSN: 1863-2661
Titre abrégé: Brain Struct Funct
Pays: Germany
ID NLM: 101282001
Informations de publication
Date de publication:
16 Jul 2024
16 Jul 2024
Historique:
received:
19
04
2024
accepted:
06
07
2024
medline:
16
7
2024
pubmed:
16
7
2024
entrez:
16
7
2024
Statut:
aheadofprint
Résumé
Behavioral differences between men and women have been studied extensively, as have differences in brain anatomy. However, most studies have focused on differences in gray matter, while white matter has been much less studied. We conducted a comprehensive study of 77 deep white matter tracts to analyze their volumetric and microstructural variability between men and women in the full Human Connectome Project (HCP) cohort of 1065 healthy individuals aged 22-35 years. We found a significant difference in total brain volume between men and women (+ 12.6% in men), consistent with the literature. 16 tracts showed significant volumetric differences between men and women, one of which stood out due to a larger effect size: the corpus callosum genu, which was larger in women (+ 7.3% in women, p = 5.76 × 10
Identifiants
pubmed: 39012482
doi: 10.1007/s00429-024-02833-0
pii: 10.1007/s00429-024-02833-0
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : European Union's Horizon 2020 Framework Program for Research and Innovation
ID : 945539
Informations de copyright
© 2024. The Author(s).
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