Automatic assessment of body composition in children with lymphoma: results of a [

Adipose tissue Children Magnetic resonance imaging Muscle lymphoma

Journal

European radiology
ISSN: 1432-1084
Titre abrégé: Eur Radiol
Pays: Germany
ID NLM: 9114774

Informations de publication

Date de publication:
16 Jul 2024
Historique:
received: 09 01 2024
accepted: 27 06 2024
revised: 28 04 2024
medline: 16 7 2024
pubmed: 16 7 2024
entrez: 16 7 2024
Statut: aheadofprint

Résumé

To use Dixon-MR images extracted from [ Pediatric patients with lymphoma examined by [ Thirty-seven patients (mean age ± SD 14 ± 3-years-old; 20 females) matched the inclusion criteria. After chemotherapy (interval between the two PET/MR scans, 56-80 days; median 65 days), muscle volume significantly decreased (629 ± 259 cm The proposed method demonstrated that pediatric patients with lymphoma undergo muscle loss and an increase of subcutaneous fat during treatment. The proposed automatic and volumetric MR-based assessment of body composition in children with lymphoma can be used to monitor the effect of chemotherapy and may guide tailored exercise programs during chemotherapy. T1w Dixon images can be used for the automatic segmentation and quantification of body composition. Muscle and subcutaneous fat volume do not act as predictors of the response to treatment in children with lymphoma. Chemotherapy induces changes in body composition in children with lymphoma.

Identifiants

pubmed: 39012528
doi: 10.1007/s00330-024-10957-4
pii: 10.1007/s00330-024-10957-4
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s).

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Auteurs

Chiara Giraudo (C)

Unit of Advanced Clinical and Translational Imaging, Department of Cardiac, Thoracic, Vascular Sciences and Public Health-DCTV, University of Padova, Padova, Italy. chiara.giraudo@unipd.it.

Celeste Cavallin (C)

Hospital of Cittadella, Cittadella, Italy.

Marta Pillon (M)

Pediatric Hematology, Oncology and Stem Cell Transplant Division, Department of Woman's and Child's Health, University of Padua, Padua, Italy.

Elisa Carraro (E)

Pediatric Hematology, Oncology and Stem Cell Transplant Division, Department of Woman's and Child's Health, University of Padua, Padua, Italy.

Giulia Fichera (G)

Pediatric Radiology Unit, Azienda Ospedale-Università Padova, Padova, Italy.

Diego Cecchin (D)

Nuclear Medicine Unit, Department of Medicine-DIMED, University of Padova, Padova, Italy.

Pietro Zucchetta (P)

Nuclear Medicine Unit, Department of Medicine-DIMED, University of Padova, Padova, Italy.

Classifications MeSH