Comparison of the Cosmetic Efficacy of Extractum Cepae and Silicone-Based Gel in Upper Blepharoplasty.
Journal
The Journal of craniofacial surgery
ISSN: 1536-3732
Titre abrégé: J Craniofac Surg
Pays: United States
ID NLM: 9010410
Informations de publication
Date de publication:
17 Jul 2024
17 Jul 2024
Historique:
received:
04
06
2024
accepted:
10
06
2024
medline:
17
7
2024
pubmed:
17
7
2024
entrez:
17
7
2024
Statut:
aheadofprint
Résumé
Upper eyelid blepharoplasty is one of the most common surgeries performed worldwide. However, an important problem after surgery is scar formation. The authors aimed to compare the efficacy of extractum cepae and silicone-based gels on postoperative scar appearance in patients undergoing upper eyelid blepharoplasty. After suture removal, patients were divided into 3 groups: group 1 [n=82, extractum cepae, sodium heparin, and allantoin mixture, Contractubex Gel (Merz Pharmaceuticals, Frankfurt, Germany)], group 2 [n=81, silicone-based gel (Dermatix Ultra Silicone Gel, Menarini, Singapore)], and group 3 (n=77, no additional treatment). Patients used the topical gels twice daily. All evaluations were performed on color photographs by 2 physicians during the postoperative first and third months. The mean visual analog scale scores were significantly higher in all 3 groups in the postoperative first month (4.39±2.03, 4.41±2.57, and 4.33±2.46, respectively) compared with the postoperative third month (2.22±1.24, 2.15±1.38, and 2.29±1.47, respectively) (P=0.014, 0.037, and 0.026, respectively). The "Is the scar more stiff" score was higher in the postoperative first month compared with the third month. In conclusion, blepharoplasty scars improved up to the postoperative third month, but the topical gels used did not significantly improve the cosmetic appearance of blepharoplasty scars compared with the control group.
Sections du résumé
BACKGROUND
BACKGROUND
Upper eyelid blepharoplasty is one of the most common surgeries performed worldwide. However, an important problem after surgery is scar formation. The authors aimed to compare the efficacy of extractum cepae and silicone-based gels on postoperative scar appearance in patients undergoing upper eyelid blepharoplasty.
METHODS
METHODS
After suture removal, patients were divided into 3 groups: group 1 [n=82, extractum cepae, sodium heparin, and allantoin mixture, Contractubex Gel (Merz Pharmaceuticals, Frankfurt, Germany)], group 2 [n=81, silicone-based gel (Dermatix Ultra Silicone Gel, Menarini, Singapore)], and group 3 (n=77, no additional treatment). Patients used the topical gels twice daily. All evaluations were performed on color photographs by 2 physicians during the postoperative first and third months.
RESULTS
RESULTS
The mean visual analog scale scores were significantly higher in all 3 groups in the postoperative first month (4.39±2.03, 4.41±2.57, and 4.33±2.46, respectively) compared with the postoperative third month (2.22±1.24, 2.15±1.38, and 2.29±1.47, respectively) (P=0.014, 0.037, and 0.026, respectively). The "Is the scar more stiff" score was higher in the postoperative first month compared with the third month.
CONCLUSIONS
CONCLUSIONS
In conclusion, blepharoplasty scars improved up to the postoperative third month, but the topical gels used did not significantly improve the cosmetic appearance of blepharoplasty scars compared with the control group.
Identifiants
pubmed: 39016346
doi: 10.1097/SCS.0000000000010472
pii: 00001665-990000000-01767
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2024 by Mutaz B. Habal, MD.
Déclaration de conflit d'intérêts
The authors report no conflicts of interest.
Références
Arno AI, Gauglitz GG, Barret JP, et al. Up-to-date approach to manage keloids and hypertrophic scars: a useful guide. Burns 2014;40:1255–1266
Kalasho BD, Kikuchi R, Zoumalan CI. Silicone-based scar cream for post upper eyelid blepharoplasty-associated cicatricial and hypertrophic scarring. J Drugs Dermatol 2019;18:440–446
Murdock J, Sayed MS, Tavakoli M, et al. Safety and efficacy of a growth factor and cytokine-containing topical product in wound healing and incision scar management after upper eyelid blepharoplasty: a prospective split-face study. Clin Ophthalmol 2016;10:1223–1228
Owji N, Khademi B, Khalili MR. Effectiveness of topical onion extract gel in the cosmetic appearance of blepharoplasty scar. J Clin Aesthet Dermatol 2018;11:31–35
Ma YK, Lin SH, Lin YH. Comparison of LeniScar Silicone Stick (AnsCare) with traditional silicone gel (Dermatix Ultra) in wound scar prevention and removal. Ann Plast Surg 2023;90(Suppl 1):S103–S110
Hassanpour SE, Farnoush N, Karami MY, et al. The effect of silicone gel versus contractubex gel on the upper-extremity postsurgical scars: a randomized, double-blinded, controlled trial. Med J Islam Repub Iran 2020;34:146
Yang X, Lohsiriwat V, Chang FCS, et al. Real-world management of abnormal scarring using topical silicone gel: expert consensus and case series from the Asian SCARS Expert Group. Drugs Context 2023;12:2023-4-3
Güngör ES, Güzel D, Zebitay AG, et al. The efficacy of onion extract in the management of subsequent abdominal hypertrophic scar formation. J Wound Care 2020;29:612–616
Minaev SV, Vladimirova OV, Kirgizov IV, et al. Multicenter study of the effectiveness of antiscar therapy in patients at different age periods. Khirurgiia (Mosk) 2020;9:51–58