Molecular epidemiology of Acinetobacter baumannii during COVID-19 at a hospital in northern China.
Acinetobacter baumannii
/ genetics
Humans
COVID-19
/ epidemiology
China
/ epidemiology
Acinetobacter Infections
/ epidemiology
Molecular Epidemiology
beta-Lactamases
/ genetics
SARS-CoV-2
/ genetics
Anti-Bacterial Agents
/ pharmacology
Carbapenems
/ pharmacology
Microbial Sensitivity Tests
Bacterial Proteins
/ genetics
Hospitals
Drug Resistance, Multiple, Bacterial
/ genetics
Plasmids
/ genetics
Acinetobacter baumannii
Molecular epidemiology
Resistance mechanisms
ST540
Tn2009
Journal
Annals of clinical microbiology and antimicrobials
ISSN: 1476-0711
Titre abrégé: Ann Clin Microbiol Antimicrob
Pays: England
ID NLM: 101152152
Informations de publication
Date de publication:
18 Jul 2024
18 Jul 2024
Historique:
received:
21
09
2023
accepted:
10
06
2024
medline:
19
7
2024
pubmed:
19
7
2024
entrez:
18
7
2024
Statut:
epublish
Résumé
The wide spread of carbapenem-resistance clones of Acinetobacter baumannii has made it a global public problem. Some studies have shown that the prevalence of Acinetobacter baumannii clones can change over time. However, few studies with respect to the change of epidemiological clones in Acinetobacter baumannii during Corona Virus Disease 2019 (COVID-19) were reported. This study aims to investigate the molecular epidemiology and resistance mechanisms of Acinetobacter baumannii during COVID-19. A total of 95 non-replicated Acinetobacter baumannii isolates were enrolled in this study, of which 60.0% (n = 57) were identified as carbapenem-resistant Acinetobacter baumannii (CRAB). The positive rate of the bla The prevalent clones of Acinetobacter baumannii in our organization have changed during COVID-19, which was different from that of China. ST540 strains which carried multiple drug-resistant mobile elements was spreading, indicating that it is essential to strengthen the molecular epidemiology of Acinetobacter baumannii.
Sections du résumé
BACKGROUND
BACKGROUND
The wide spread of carbapenem-resistance clones of Acinetobacter baumannii has made it a global public problem. Some studies have shown that the prevalence of Acinetobacter baumannii clones can change over time. However, few studies with respect to the change of epidemiological clones in Acinetobacter baumannii during Corona Virus Disease 2019 (COVID-19) were reported. This study aims to investigate the molecular epidemiology and resistance mechanisms of Acinetobacter baumannii during COVID-19.
RESULTS
RESULTS
A total of 95 non-replicated Acinetobacter baumannii isolates were enrolled in this study, of which 60.0% (n = 57) were identified as carbapenem-resistant Acinetobacter baumannii (CRAB). The positive rate of the bla
CONCLUSION
CONCLUSIONS
The prevalent clones of Acinetobacter baumannii in our organization have changed during COVID-19, which was different from that of China. ST540 strains which carried multiple drug-resistant mobile elements was spreading, indicating that it is essential to strengthen the molecular epidemiology of Acinetobacter baumannii.
Identifiants
pubmed: 39026334
doi: 10.1186/s12941-024-00716-0
pii: 10.1186/s12941-024-00716-0
doi:
Substances chimiques
beta-Lactamases
EC 3.5.2.6
Anti-Bacterial Agents
0
Carbapenems
0
Bacterial Proteins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
63Subventions
Organisme : the State Key Laboratory of Pathogen and Biosecurity of China
ID : SKLPBS2228
Informations de copyright
© 2024. The Author(s).
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