Whitening toothpastes with hydrogen peroxide concentrations vs. at-home bleaching.


Journal

Clinical oral investigations
ISSN: 1436-3771
Titre abrégé: Clin Oral Investig
Pays: Germany
ID NLM: 9707115

Informations de publication

Date de publication:
20 Jul 2024
Historique:
received: 29 05 2024
accepted: 05 07 2024
medline: 20 7 2024
pubmed: 20 7 2024
entrez: 19 7 2024
Statut: epublish

Résumé

To evaluate the effect of whitening toothpastes with different hydrogen peroxide (HP) concentrations on HP permeability, color change, and physicochemical properties, compared to at-home bleaching treatment. Forty-nine premolars were randomized into seven groups (n = 7): untreated (control); at-home bleaching with 10% carbamide peroxide gel (AH; 10% CP) with 14 and 28 applications of 180 min each (AH [14 × 180 min] and AH [28 × 180 min]); three whitening toothpastes (3% HP; 4% HP and 5% HP) and 10% CP brushed 28 times for 90 s each (TB [28 × 90 s]). HP permeability was measured using a UV-VIS spectrophotometer and color change by a digital spectrophotometer (ΔE 4% HP group showed acidic pH, the lowest viscosity and the highest HP concentration into the pulp chamber (p < 0.05). The 10% CP groups had lower HP in the pulp chamber and greater color change than other groups (p < 0.05), except the 5% HP group in ΔE Whitening toothpaste with up to 5% HP resulted in higher HP permeability and less color change compared to 10% CP. Higher HP commercial concentrations in toothpaste increased whitening effect; however, acidic pH toothpastes exhibited greater HP permeability. Whitening toothpastes with high hydrogen peroxide concentrations were less effective than at-home bleaching, resulting in less color change and greater permeability of hydrogen peroxide, potentially increasing the risk of tooth sensitivity.

Identifiants

pubmed: 39030259
doi: 10.1007/s00784-024-05823-y
pii: 10.1007/s00784-024-05823-y
doi:

Substances chimiques

Hydrogen Peroxide BBX060AN9V
Toothpastes 0
Tooth Bleaching Agents 0
Carbamide Peroxide 31PZ2VAU81
Urea 8W8T17847W

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

436

Subventions

Organisme : Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
ID : 001
Organisme : Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
ID : 001
Organisme : Conselho Nacional de Desenvolvimento Científico e Tecnológico
ID : 304817/2021-0
Organisme : Conselho Nacional de Desenvolvimento Científico e Tecnológico
ID : 308286/2019-7
Organisme : Conselho Nacional das Fundações Estaduais de Amparo à Pesquisa
ID : 009/21

Informations de copyright

© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Références

Bonafé E, Rezende M, Machado MM, Lima SNL, Fernandez E, Baldani MMP, Reis A, Loguercio AD, Bandeca MC (2021) Personality traits, psychosocial effects and quality of life of patients submitted to dental bleaching. BMC Oral Health 21(1):7. https://doi.org/10.1186/s12903-020-01370-6
doi: 10.1186/s12903-020-01370-6 pubmed: 33407342 pmcid: 7789155
de Geus JL, Wambier LM, Kossatz S, Loguercio AD, Reis A (2016) At-home vs In-office bleaching: a systematic review and Meta-analysis. Oper Dent 41(4):341–356. https://doi.org/10.2341/15-287-LIT
doi: 10.2341/15-287-LIT pubmed: 27045285
Barbosa LMM, Amâncio Filha MBG, Leite JVC, Santos JVDN, De Medeiros JM, De Oliveira ILM, Pecho OE, Meireles SS, Lima RBW (2024) Over-the-counter products in tooth bleaching: a scoping review. J Dent 145:104989. https://doi.org/10.1016/j.jdent.2024.104989
doi: 10.1016/j.jdent.2024.104989 pubmed: 38582435
de Oliveira MN, Vidigal MTC, Vieira W, Lins-Candeiro CL, Oliveira LM, Nascimento GG, da Silva GR, Paranhos LR (2024) Assessment of color changes and adverse effects of over-the-counter bleaching protocols: a systematic review and network meta-analysis. Clin Oral Investig 28(3):189. https://doi.org/10.1007/s00784-024-05595-5
doi: 10.1007/s00784-024-05595-5 pubmed: 38430338
Kwon SR, Wertz PW (2015) Review of the mechanism of tooth whitening. J Esthet Restor Dent 27(5):240–257. https://doi.org/10.1111/jerd.12152
doi: 10.1111/jerd.12152 pubmed: 25969131
Kim YM, Ha AN, Kim JW, Kim SJ (2018) Double-blind randomized study to evaluate the safety and efficacy of over-the-counter tooth-whitening agents containing 2.9% hydrogen peroxide. Oper Dent 43(3):272–281. https://doi.org/10.2341/16-379-C
doi: 10.2341/16-379-C pubmed: 29513635
Jurema AL, Claudino ES, Torres CR, Bresciani E, Caneppele TM (2018) Effect of over-the-counter whitening products associated or not with 10% carbamide peroxide on Color Change and Microhardness: in vitro study. J Contemp Dent Pract 19(4):359–366
doi: 10.5005/jp-journals-10024-2267 pubmed: 29728537
Meireles SS, de Sousa JP, Lins RBE, Sampaio FC (2021) Efficacy of whitening toothpaste containing blue covarine: a double-blind controlled randomized clinical trial. J Esthet Restor Dent 33(2):341–350. https://doi.org/10.1111/jerd.12605
doi: 10.1111/jerd.12605 pubmed: 32820846
Barbosa LMM, Carneiro TS, Favoreto MW, Borges CPF, Reis A, Loguercio AD, Meireles SS (2024) Effect of whitening toothpastes with different hydrogen peroxide concentrations: penetration into the pulp chamber and color change. J Dent 144:104951. https://doi.org/10.1016/j.jdent.2024.104951
doi: 10.1016/j.jdent.2024.104951 pubmed: 38508441
Markowitz K (2010) Pretty painful: why does tooth bleaching hurt? Med Hypotheses 74(5):835–840. https://doi.org/10.1016/j.mehy.2009.11.044
doi: 10.1016/j.mehy.2009.11.044 pubmed: 20045265
Ubaldini AL, Baesso ML, Medina Neto A, Sato F, Bento AC, Pascotto RC (2013) Hydrogen peroxide diffusion dynamics in dental tissues. J Dent Res 92(7):661–665. https://doi.org/10.1177/0022034513488893
doi: 10.1177/0022034513488893 pubmed: 23632810
Rezende M, Loguercio AD, Kossatz S, Reis A (2016) Predictive factors on the efficacy and risk/intensity of tooth sensitivity of dental bleaching: a multi regression and logistic analysis. J Dent 45:1–6. https://doi.org/10.1016/j.jdent.2015.11.003
doi: 10.1016/j.jdent.2015.11.003 pubmed: 26612623
Casado BGS, Moraes SLD, Souza GFM, Guerra CMF, Souto-Maior JR, Lemos CAA, Vasconcelos BCE, Pellizzer EP (2018) Efficacy of Dental bleaching with whitening dentifrices: a systematic review. Int J Dent 2018:7868531. https://doi.org/10.1155/2018/7868531
doi: 10.1155/2018/7868531 pubmed: 30510576 pmcid: 6232812
Vaz VTP, Jubilato DP, Oliveira MRM, Bortolatto JF, Floros MC, Dantas AAR, Oliveira Junior OB (2019) Whitening toothpaste containing activated charcoal, blue covarine, hydrogen peroxide or microbeads: which one is the most effective? J Appl Oral Sci 27:e20180051. https://doi.org/10.1590/1678-7757-2018-0051
doi: 10.1590/1678-7757-2018-0051 pubmed: 30673027 pmcid: 6438662
Kim HJ, Jang JH, Choi D, Kim J, Shim JH, Kim DS (2020) Bleaching toothpaste with two different concentrations of hydrogen peroxide: a randomized double-blinded clinical trial. J Dent 103:103508. https://doi.org/10.1016/j.jdent.2020.103508
doi: 10.1016/j.jdent.2020.103508 pubmed: 33121984
Vladislavic NZ, Tadin A, Gavic L, Jerkovic D, Franic I, Verzak Z (2022) In vivo evaluation of whitening toothpaste efficiency and patient treatment satisfaction: a randomized controlled trial. Clin Oral Investig 26(1):739–750. https://doi.org/10.1007/s00784-021-04052-x
doi: 10.1007/s00784-021-04052-x pubmed: 34245356
Shamel M, Al-Ankily MM, Bakr MM (2019) Influence of different types of whitening tooth pastes on the tooth color, enamel surface roughness and enamel morphology of human teeth. F1000Res 8:1764. https://doi.org/10.12688/f1000research.20811.1
doi: 10.12688/f1000research.20811.1 pubmed: 31839926 pmcid: 6900807
Lima LC, Carvalho AO, Bezerra SJC, Garcia RM, Caneppele TMF, Borges AB, Scaramucci T (2023) Tooth color change promoted by different whitening toothpastes under alternate cycles of staining and brushing. J Dent 132:104498. https://doi.org/10.1016/j.jdent.2023.104498
doi: 10.1016/j.jdent.2023.104498 pubmed: 36963626
de Geus JL, Wambier LM, Boing TF, Loguercio AD, Reis A (2018) At-home bleaching with 10% vs more concentrated Carbamide Peroxide gels: a systematic review and Meta-analysis. Oper Dent 43(4):E210–E222. https://doi.org/10.2341/17-222-L
doi: 10.2341/17-222-L pubmed: 29949477
Pérez Mdel M, Ghinea R, Rivas MJ, Yebra A, Ionescu AM, Paravina RD, Herrera LJ (2016) Development of a customized whiteness index for dentistry based on CIELAB color space. Dent Mater 32(3):461–467. https://doi.org/10.1016/j.dental.201
doi: 10.1016/j.dental.201 pubmed: 26778404
Mena-Serrano AP, Parreiras SO, do Nascimento EM, Borges CP, Berger SB, Loguercio AD, Reis A (2015) Effects of the concentration and composition of in-office bleaching gels on hydrogen peroxide penetration into the pulp chamber. Oper Dent 40(2):E76–E82. https://doi.org/10.2341/13-352-L
doi: 10.2341/13-352-L pubmed: 25535786
Cordeiro DCF, Favoreto MW, Centenaro GG, Gumy FN, Loguercio AD, Borges CPF, Reis A (2024) At-home bleaching with carbamide peroxide with concentrations below 10%: bleaching efficacy and permeability in the pulp chamber. Clin Oral Investig 28(4):224. https://doi.org/10.1007/s00784-024-05604-7
doi: 10.1007/s00784-024-05604-7 pubmed: 38509406
Parreiras SO, Favoreto MW, Cruz GP, Gomes A, Borges CPF, Loguercio AD, Reis A (2020) Initial and pulp chamber concentration of hydrogen peroxide using different bleaching products. Braz Dent Sci 23(2). https://doi.org/10.14295/bds.2020.v23i2.1942
Kim JH, Kim S, Truong VM, Lee JW, Park YS (2022) Is whitening toothpaste safe for dental health? RDA-PE method. Dent Mater J 41(5):731–740. https://doi.org/10.4012/dmj.2021-303
doi: 10.4012/dmj.2021-303 pubmed: 35793939
Favoreto MW, Parreiras SO, Wendlinger M, Carneiro TS, Lenhani MI, Borges CPF, Reis A, Loguercio AD (2024) Evaluation of hydrogen peroxide permeability, color change, and physical-chemical properties on the in-office dental bleaching with different mixing tip. J Esthet Restor Dent 36(3):460–468. https://doi.org/10.1111/jerd.13134
doi: 10.1111/jerd.13134 pubmed: 37728145
Favoreto MW, Madureira MP, Hass V, Maran BM, Parreiras SO, Borges CPF, Reis A, Loguercio AD (2021) A novel carbamide peroxide polymeric nanoparticle bleaching gel: Color change and hydrogen peroxide penetration inside the pulp cavity. J Esthet Restor Dent 33(2):277–283. https://doi.org/10.1111/jerd.12652
doi: 10.1111/jerd.12652 pubmed: 32949453
Comission Internationale de l’éclairage (1977) CIE recommendations on Uniform Color spaces, Color-Difference equations, and Metric Color terms. Color Res Appl 2:5–6. https://doi.org/10.1002/j.1520-6378.1977.tb00102.x
doi: 10.1002/j.1520-6378.1977.tb00102.x
Luo MR, Cui G, Rigg B (2001) The development of the CIE 2000 colour-difference formula: CIEDE2000. Color Res Appl 26:340–350. https://doi.org/10.1002/col.1049
doi: 10.1002/col.1049
Paravina RD, Pérez MM, Ghinea R (2019) Acceptability and perceptibility thresholds in dentistry: a comprehensive review of clinical and research applications. J Esthet Restor Dent 31(2):103–112. https://doi.org/10.1111/jerd.12465
doi: 10.1111/jerd.12465 pubmed: 30891913
Pérez MM, Herrera LJ, Carrillo F, Pecho OE, Dudea D, Gasparik C, Ghinea R, Bona AD (2019) Whiteness difference thresholds in dentistry. Dent Mater 35(2):292–297. https://doi.org/10.1016/j.dental.2018.11.022
doi: 10.1016/j.dental.2018.11.022 pubmed: 30527588
Devila A, Lasta R, Zanella L, Agnol MD, Rodrigues-Junior SA (2020) Efficacy and adverse effects of whitening dentifrices compared with other products: a systematic review and Meta-analysis. Oper Dent 45(2):E77–E90. https://doi.org/10.2341/18-298-L
doi: 10.2341/18-298-L pubmed: 31738695
Jamwal N, Rao A, Shenoy R, Pai M, Ks A, Br A (2022) Effect of whitening toothpaste on surface roughness and microhardness of human teeth: a systematic review and meta-analysis. F1000Res 11:22. https://doi.org/10.12688/f1000research.76180.3
doi: 10.12688/f1000research.76180.3 pubmed: 35265322 pmcid: 8874033
Acuña ED, Parreiras SO, Favoreto MW, Cruz GP, Gomes A, Borges CPF, Loguercio AD, Reis A (2022) In-office bleaching with a commercial 40% hydrogen peroxide gel modified to have different pHs: Color change, surface morphology, and penetration of hydrogen peroxide into the pulp chamber. J Esthet Restor Dent 34(2):322–327. https://doi.org/10.1111/jerd.12453
doi: 10.1111/jerd.12453 pubmed: 30790402
Kwon SR, Pallavi F, Shi Y, Oyoyo U, Mohraz A, Li Y (2018) Effect of bleaching gel viscosity on tooth whitening efficacy and pulp Chamber Penetration: an in Vitro Study. Oper Dent 43(3):326–334. https://doi.org/10.2341/17-099-L
doi: 10.2341/17-099-L pubmed: 29676980
da Silva KL, Favoreto MW, Centenaro GG, Bernardi LG, Borges CPF, Reis A, Loguercio AD (2023) Can all highly concentrated in-office bleaching gels be used as a single-application? Clin Oral Investig 27(7):3663–3671. https://doi.org/10.1007/s00784-023-04980-w
doi: 10.1007/s00784-023-04980-w pubmed: 37017758
Cheng CY, Balsandorj Z, Hao Z, Pan L (2020) High-precision measurement of pH in the full toothpaste using NMR chemical shift. J Magn Reson 317:106771. https://doi.org/10.1016/j.jmr.2020.106771
doi: 10.1016/j.jmr.2020.106771 pubmed: 32629341
Dahl JE, Pallesen U (2003) Tooth bleaching–a critical review of the biological aspects. Crit Rev Oral Biol Med 14(4):292–304. https://doi.org/10.1177/154411130301400406
doi: 10.1177/154411130301400406 pubmed: 12907697
Xu B, Li Q, Wang Y (2011) Effects of pH values of hydrogen peroxide bleaching agents on enamel surface properties. Oper Dent 36(5):554–562. https://doi.org/10.2341/11-045-1
doi: 10.2341/11-045-1 pubmed: 21859312
Sa Y, Sun L, Wang Z, Ma X, Liang S, Xing W, Jiang T, Wang Y (2013) Effects of two in-office bleaching agents with different pH on the structure of human enamel: an in situ and in vitro study. Oper Dent 38(1):100–110. https://doi.org/10.2341/11-173-L
doi: 10.2341/11-173-L pubmed: 22917440
Torres C, Moecke SE, Mafetano A, Cornélio LF, Di Nicoló R, Borgesd AB (2022) Influence of viscosity and thickener on the effects of bleaching gels. Oper Dent 47(3):E119–E130. https://doi.org/10.2341/20-309-L
doi: 10.2341/20-309-L pubmed: 35649221
Ahuja A, Potanin A (2018) Rheological and sensory properties of toothpastes. Rheol Acta 57:459–471. https://doi.org/10.1007/s00397-018-1090-z
doi: 10.1007/s00397-018-1090-z
Soeteman GD, Valkenburg C, Van der Weijden GA, Van Loveren C, Bakker E, Slot DE (2018) Whitening dentifrice and tooth surface discoloration-a systematic review and meta-analysis. Int J Dent Hyg 16(1):24–35. https://doi.org/10.1111/idh.12289
doi: 10.1111/idh.12289 pubmed: 28573755
Pintado-Palomino K, Vasconcelos CV, Silva RJ, Fressatti AL, Motta BJ, Pires-DE-Souza FC, Tirapelli C (2016) Effect of whitening dentifrices: a double-blind randomized controlled trial. Braz Oral Res 30(1):e82. https://doi.org/10.1590/1807-3107BOR-2016.vol30.0082
Paravina RD, Ghinea R, Herrera LJ, Bona AD, Igiel C, Linninger M, Sakai M, Takahashi H, Tashkandi E, Perez Mdel M (2015) Color difference thresholds in dentistry. J Esthet Restor Dent 27(Suppl 1):S1–9. https://doi.org/10.1111/jerd.12149
doi: 10.1111/jerd.12149 pubmed: 25886208
Gómez-Polo C, Portillo Muñoz M, Lorenzo Luengo MC, Vicente P, Galindo P, Martín Casado AM (2016) Comparison of the CIELab and CIEDE2000 color difference formulas. J Prosthet Dent 115(1):65–70. https://doi.org/10.1016/j.prosdent.2015.07.001
doi: 10.1016/j.prosdent.2015.07.001 pubmed: 26412001
Martini EC, Favoreto MW, Coppla FM, Loguercio AD, Reis A (2020) Evaluation of reservoirs in bleaching trays for at-home bleaching: a split-mouth single-blind randomized controlled equivalence trial. J Appl Oral Sci 28:e20200332. https://doi.org/10.1590/1678-7757-2020-0332
doi: 10.1590/1678-7757-2020-0332 pubmed: 32813842 pmcid: 7433864
Sutil E, da Silva KL, Terra RMO, Burey A, Rezende M, Reis A, Loguercio AD (2022) Effectiveness and adverse effects of at-home dental bleaching with 37% versus 10% carbamide peroxide: a randomized, blind clinical trial. J Esthet Restor Dent 34(2):313–321. https://doi.org/10.1111/jerd.12677
doi: 10.1111/jerd.12677 pubmed: 33169944
Pavani CC, Fagundes TC, Sundfeld D, Santin GC, Machado LS, Bertoz APM, Schott TC, Sundfeld RH (2023) Influence of daily usage times on patients’ compliance during at-home bleaching: a randomized clinical trial. J Appl Oral Sci 31:e20230181. https://doi.org/10.1590/1678-7757-2023-0181
doi: 10.1590/1678-7757-2023-0181 pubmed: 37820182 pmcid: 10519669
Torres CR, Wiegand A, Sener B, Attin T (2010) Influence of chemical activation of a 35% hydrogen peroxide bleaching gel on its penetration and efficacy: in vitro study. J Dent 38(10):838–846. https://doi.org/10.1016/j.jdent.2010.07.002
doi: 10.1016/j.jdent.2010.07.002 pubmed: 20633597
Kiyuna RC, Martins LM, Hanzen TA, Reis A, Loguercio AD, Silva LM (2021) Comparison of the effect of agitation on whitening and tooth sensitivity of In-Office bleaching: a Randomized Clinical Trial. Oper Dent 46(2):143–150. https://doi.org/10.2341/19-223-C
doi: 10.2341/19-223-C pubmed: 34464978

Auteurs

Laryssa Mylenna Madruga Barbosa (LMM)

Department of Restorative Dentistry, School of Dentistry, State University of Ponta Grossa, Ponta Grossa, Paraná, Brazil.

Taynara de Souza Carneiro (T)

Department of Restorative Dentistry, School of Dentistry, State University of Ponta Grossa, Ponta Grossa, Paraná, Brazil.
Health Sciences Faculty, IDIBO research group, Rey Juan Carlos University, Alcorcón, Madrid, Spain.

Michael Willian Favoreto (MW)

Department of Restorative Dentistry, School of Dentistry, State University of Ponta Grossa, Ponta Grossa, Paraná, Brazil.
School of Dentistry, Tuiuti University of Parana, Curitiba, Paraná, Brazil.

Christiane Philippini Ferreira Borges (CPF)

Department of Chemistry, State University of Ponta Grossa, Ponta Grossa, Paraná, Brazil.

Alessandra Reis (A)

Department of Restorative Dentistry, School of Dentistry, State University of Ponta Grossa, Ponta Grossa, Paraná, Brazil.

Sônia Saeger Meireles (SS)

Department of Restorative Dentistry, School of Dentistry, Federal University of Paraíba, João Pessoa, Paraíba, Brazil.

Alessandro D Loguercio (AD)

Department of Restorative Dentistry, School of Dentistry, State University of Ponta Grossa, Ponta Grossa, Paraná, Brazil. aloguercio@hotmail.com.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH