Salvage breast conserving surgery and re-irradiation with intraoperative electrons for recurrent breast cancer: a multicentric study on behalf of AIRO (Italian Association of Radiotherapy and clinical Oncology).
breast cancer
intraoperative radiotherapy
local recurrence
partial breast re-irradiation
repeat quadrantectomy
salvage treatment
Journal
Practical radiation oncology
ISSN: 1879-8519
Titre abrégé: Pract Radiat Oncol
Pays: United States
ID NLM: 101558279
Informations de publication
Date de publication:
18 Jul 2024
18 Jul 2024
Historique:
received:
05
12
2023
revised:
30
04
2024
accepted:
21
05
2024
medline:
21
7
2024
pubmed:
21
7
2024
entrez:
20
7
2024
Statut:
aheadofprint
Résumé
Intraoperative radiotherapy with electrons (IOERT) may represent a viable choice for partial breast re-irradiation (rePBI) after repeat quadrantectomy for local recurrence (LR) for primary breast cancer (BC) in lieu of mastectomy. A database collecting data on rePBI with IOERT from 8 Italian centres was set up in 2016- 2018, providing data on cumulative incidence (CumI) of 2 2ndLR CumI was within the range of the literature, but higher than expected, opening questions on radiation field extension and fractionation schedule. Since a 2ndLR worsened the outcome, salvage modality must be carefully planned.
Identifiants
pubmed: 39032597
pii: S1879-8500(24)00160-7
doi: 10.1016/j.prro.2024.05.012
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2024. Published by Elsevier Inc.