Delivering Microrobots in the Musculoskeletal System.
Magnetic actuation
Microrobot
Microrobotic systems
Musculoskeletal system
Targeted delivery
Journal
Nano-micro letters
ISSN: 2150-5551
Titre abrégé: Nanomicro Lett
Pays: Germany
ID NLM: 101727940
Informations de publication
Date de publication:
22 Jul 2024
22 Jul 2024
Historique:
received:
08
04
2024
accepted:
16
06
2024
medline:
22
7
2024
pubmed:
22
7
2024
entrez:
22
7
2024
Statut:
epublish
Résumé
Disorders of the musculoskeletal system are the major contributors to the global burden of disease and current treatments show limited efficacy. Patients often suffer chronic pain and might eventually have to undergo end-stage surgery. Therefore, future treatments should focus on early detection and intervention of regional lesions. Microrobots have been gradually used in organisms due to their advantages of intelligent, precise and minimally invasive targeted delivery. Through the combination of control and imaging systems, microrobots with good biosafety can be delivered to the desired area for treatment. In the musculoskeletal system, microrobots are mainly utilized to transport stem cells/drugs or to remove hazardous substances from the body. Compared to traditional biomaterial and tissue engineering strategies, active motion improves the efficiency and penetration of local targeting of cells/drugs. This review discusses the frontier applications of microrobotic systems in different tissues of the musculoskeletal system. We summarize the challenges and barriers that hinder clinical translation by evaluating the characteristics of different microrobots and finally point out the future direction of microrobots in the musculoskeletal system.
Identifiants
pubmed: 39037551
doi: 10.1007/s40820-024-01464-8
pii: 10.1007/s40820-024-01464-8
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
251Informations de copyright
© 2024. The Author(s).
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