Targeting erythroid progenitor cells for cancer immunotherapy.
cancer
erythroid progenitor cells
extramedullary hematopoiesis
immunotherapy
targeting strategies
Journal
International journal of cancer
ISSN: 1097-0215
Titre abrégé: Int J Cancer
Pays: United States
ID NLM: 0042124
Informations de publication
Date de publication:
22 Jul 2024
22 Jul 2024
Historique:
revised:
05
06
2024
received:
06
11
2023
accepted:
10
06
2024
medline:
23
7
2024
pubmed:
23
7
2024
entrez:
23
7
2024
Statut:
aheadofprint
Résumé
Immunotherapy, especially immune checkpoint blockade therapy, represents a major milestone in the history of cancer therapy. However, the current response rate to immunotherapy among cancer patients must be improved; thus, new strategies for sensitizing patients to immunotherapy are urgently needed. Erythroid progenitor cells (EPCs), a population of immature erythroid cells, exert potent immunosuppressive functions. As a newly recognized immunosuppressive population, EPCs have not yet been effectively targeted. In this review, we summarize the immunoregulatory mechanisms of EPCs, especially for CD45
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : National Natural Science Foundation of China
ID : 82273202
Organisme : National Natural Science Foundation of China
ID : 82072996
Organisme : National Natural Science Foundation of China
ID : 82073349
Organisme : National Key Research and Development Program of China
ID : 2022YFC2504200
Organisme : The Interdisciplinary Innovative Foundation of Wuhan University
ID : XNJC202303
Organisme : The Fundamental Research Funds for the Central Universities
ID : 2042022dx0003
Informations de copyright
© 2024 UICC.
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