Safety of immune checkpoint inhibitor rechallenge after severe immune-related adverse events: a retrospective analysis.

immune checkpoint inhibitors (ICIs) immune related adverse events (irAEs) myocarditis neurological immune-related adverse events rechallenge

Journal

Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867

Informations de publication

Date de publication:
2024
Historique:
received: 19 03 2024
accepted: 17 06 2024
medline: 23 7 2024
pubmed: 23 7 2024
entrez: 23 7 2024
Statut: epublish

Résumé

Immune checkpoint inhibitors (ICIs) present clinicians with the challenge of managing immune-related adverse events (irAEs), which can range from mild to severe due to immune system activation

Identifiants

pubmed: 39040444
doi: 10.3389/fonc.2024.1403658
pmc: PMC11260680
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1403658

Informations de copyright

Copyright © 2024 Eldani, Kostine, Faure, Lazaro, Rigothier, Hiriart, Teulières, Poullenot, Haissaguerre, Zysman, Veillon, Vergnenegre, Issa, Domblides, Mary-Prey, Beylot-Barry, Pham-Ledard, Dutriaux, Sole, Duval and Gerard.

Déclaration de conflit d'intérêts

EG: congress fees and investigator for BMS and MSD. RV: speakers’ bureau for BMS. SM-P: consultant on boards for BMS. AP-L: congress fees for BMS. CDu: Clinical investigation in trials, congress fees and member of boards for BMS, MSD. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Auteurs

Céline Eldani (C)

Department of Dermatology, Centre Hospitalier Universitaire (CHU) Bordeaux, Bordeaux, France.

Marie Kostine (M)

Department of Rheumatology, CHU Bordeaux, Bordeaux, France.

Maxime Faure (M)

Department of Cardiology, CHU Bordeaux, Bordeaux, France.

Estibaliz Lazaro (E)

Department of Internal Medicine, Haut-Leveque, Bordeaux University Hospital, Bordeaux, France.

Claire Rigothier (C)

Department of Nephrology, Transplantation, and Dialysis, Bordeaux University Hospital Center, Bordeaux, France.

Jean Baptiste Hiriart (JB)

Hepatology Unit, Bordeaux University Hospital, Bordeaux, France.

Bérénice Teulières (B)

Department of Gastroenterology and Hepatology, Centre Médico-chirurgical Magellan, Hôpital Haut-Lévêque, CHU de Bordeaux, Bordeaux, France.

Florian Poullenot (F)

Department of Gastroenterology and Hepatology, Centre Médico-chirurgical Magellan, Hôpital Haut-Lévêque, CHU de Bordeaux, Bordeaux, France.

Magalie Haissaguerre (M)

Department of Endocrinology, University Hospital of Bordeaux, Bordeaux, France.

Maeva Zysman (M)

Pulmonary Department, Pôle Cardio-thoracique, CHU de Bordeaux, Bordeaux, France.

Rémi Veillon (R)

Pulmonary Department, Pôle Cardio-thoracique, CHU de Bordeaux, Bordeaux, France.

Charlotte Vergnenegre (C)

Pulmonary Department, Pôle Cardio-thoracique, CHU de Bordeaux, Bordeaux, France.

Nahema Issa (N)

Intensive Care Unit and Infectious Disease, University Hospital Centre Bordeaux, Bordeaux, France.

Charlotte Domblides (C)

Department of Medical Oncology, Bordeaux University Hospital, Bordeaux, France.

Sorilla Mary-Prey (S)

Department of Dermatology, Centre Hospitalier Universitaire (CHU) Bordeaux, Bordeaux, France.

Marie Beylot-Barry (M)

Department of Dermatology, Centre Hospitalier Universitaire (CHU) Bordeaux, Bordeaux, France.
BRIC (BoRdeaux Institute of onCology), Institut National de la Santé et de la Recherche Médicale (INSERM), Univ. Bordeaux, Bordeaux, France.

Anne Pham-Ledard (A)

Department of Dermatology, Centre Hospitalier Universitaire (CHU) Bordeaux, Bordeaux, France.
BRIC (BoRdeaux Institute of onCology), Institut National de la Santé et de la Recherche Médicale (INSERM), Univ. Bordeaux, Bordeaux, France.

Caroline Dutriaux (C)

Department of Dermatology, Centre Hospitalier Universitaire (CHU) Bordeaux, Bordeaux, France.

Guilhem Sole (G)

AOC Referral Center for Neuromuscular Diseases, Neurology and Neuromuscular Diseases Department, FILNEMUS, University Hospitals of Bordeaux, Bordeaux, France.

Fanny Duval (F)

AOC Referral Center for Neuromuscular Diseases, Neurology and Neuromuscular Diseases Department, FILNEMUS, University Hospitals of Bordeaux, Bordeaux, France.

Emilie Gerard (E)

Department of Dermatology, Centre Hospitalier Universitaire (CHU) Bordeaux, Bordeaux, France.

Classifications MeSH