CRITICAL ANALYSIS OF HYPERCONTRACTILE WAVES VIGOR TO DEFINE HYPERCONTRACTILE ESOPHAGUS DISEASE.


Journal

Arquivos de gastroenterologia
ISSN: 1678-4219
Titre abrégé: Arq Gastroenterol
Pays: Brazil
ID NLM: 15310600R

Informations de publication

Date de publication:
2024
Historique:
received: 12 02 2024
accepted: 09 05 2024
medline: 24 7 2024
pubmed: 24 7 2024
entrez: 24 7 2024
Statut: epublish

Résumé

The current definition for hypercontractile esophagus was arbitrarily set at the uppermost range in volunteers for a specific equipment. This study aims to critically analyze the concept of hypercontractile waves to redefine hypercontractile esophagus parameters. We reviewed 500 unselected and consecutive HRM tests (5000 waves) performed in a water -perfused system. Mean distal contractility integral (DCI) was 825±1492 (0-42775) mmHg.cm.s, two standard deviations above average = 3810; 95th percentile = 2798 mmHg.cm.s. In healthy volunteers, two standard deviations above average is 4000 mmHg.cm.s, we thus suggest this value to define hypercontractile waves and define hypercontractile esophagus in a water-perfused HRM system.

Sections du résumé

BACKGROUND BACKGROUND
The current definition for hypercontractile esophagus was arbitrarily set at the uppermost range in volunteers for a specific equipment.
OBJECTIVE OBJECTIVE
This study aims to critically analyze the concept of hypercontractile waves to redefine hypercontractile esophagus parameters.
METHODS METHODS
We reviewed 500 unselected and consecutive HRM tests (5000 waves) performed in a water -perfused system.
RESULTS RESULTS
Mean distal contractility integral (DCI) was 825±1492 (0-42775) mmHg.cm.s, two standard deviations above average = 3810; 95th percentile = 2798 mmHg.cm.s.
CONCLUSION CONCLUSIONS
In healthy volunteers, two standard deviations above average is 4000 mmHg.cm.s, we thus suggest this value to define hypercontractile waves and define hypercontractile esophagus in a water-perfused HRM system.

Identifiants

pubmed: 39046006
pii: S0004-28032024000101200
doi: 10.1590/S0004-2803.24612024-022
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e24022

Auteurs

Leonardo Yuri Kasputis Zanini (LYK)

Department of Surgery, Escola Paulista de Medicina, Federal University of São Paulo, São Paulo, Brazil.

Fernando A M Herbella (FAM)

Rede D'Or São Luiz Hospitals, São Paulo, Brazil.

Marco G Patti (MG)

University of Virginia, Charlottesville, USA.

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Classifications MeSH