Safety Assessment of Polyol Phosphates as Used in Cosmetics.

Cosmetic Ingredient Cosmetic Ingredient Review Disodium Glucose Phosphate Expert Panel for Cosmetic Ingredient Safety Manganese Fructose Diphosphate Phytic Acid Phytin Polyol Phosphates Safety Sodium Mannose Phosphate Sodium Phytate Trisodium Fructose Diphosphate Trisodium Inositol Triphosphate Xylityl Phosphate Zinc Fructose Diphosphate

Journal

International journal of toxicology
ISSN: 1092-874X
Titre abrégé: Int J Toxicol
Pays: United States
ID NLM: 9708436

Informations de publication

Date de publication:
24 Jul 2024
Historique:
medline: 24 7 2024
pubmed: 24 7 2024
entrez: 24 7 2024
Statut: aheadofprint

Résumé

The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of 10 polyol phosphates. Some of the possible functions in cosmetics that are reported for this ingredient group are chelating agents, oral care agents, and skin conditioning agents. The Panel reviewed relevant data relating to the safety of these ingredients under the intended conditions of use in cosmetic formulations, and concluded that Sodium Phytate, Phytic Acid, Phytin, and Trisodium Inositol Triphosphate are safe in cosmetics in the present practices of use and concentration described in the safety assessment. The Panel also concluded that the data are insufficient to determine the safety of the following 6 ingredients as used in cosmetics: Disodium Glucose Phosphate, Manganese Fructose Diphosphate, Sodium Mannose Phosphate, Trisodium Fructose Diphosphate, Xylityl Phosphate, and Zinc Fructose Diphosphate.

Identifiants

pubmed: 39046084
doi: 10.1177/10915818241259699
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

10915818241259699

Déclaration de conflit d'intérêts

Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Auteurs

Wilbur Johnson (W)

Cosmetic Ingredient Review Former Senior Scientific Analyst/Writer.

Wilma F Bergfeld (WF)

Expert Panel for Cosmetic Ingredient Safety Member.

Donald V Belsito (DV)

Expert Panel for Cosmetic Ingredient Safety Member.

Ronald A Hill (RA)

Expert Panel for Cosmetic Ingredient Safety Former Member.

Curtis D Klaassen (CD)

Expert Panel for Cosmetic Ingredient Safety Member.

Daniel C Liebler (DC)

Expert Panel for Cosmetic Ingredient Safety Former Member.

James G Marks (JG)

Expert Panel for Cosmetic Ingredient Safety Former Member.

Ronald C Shank (RC)

Expert Panel for Cosmetic Ingredient Safety Former Member.

Thomas J Slaga (TJ)

Expert Panel for Cosmetic Ingredient Safety Member.

Paul W Snyder (PW)

Expert Panel for Cosmetic Ingredient Safety Member.

Monice Fiume (M)

Cosmetic Ingredient Review Senior Director.

Bart Heldreth (B)

Cosmetic Ingredient Review Executive Director.

Classifications MeSH