Flortaucipir PET uncovers relationships between tau and amyloid-β in primary age-related tauopathy and Alzheimer's disease.

Humans Positron-Emission Tomography / methods Alzheimer Disease / diagnostic imaging tau Proteins / metabolism Carbolines / metabolism Amyloid beta-Peptides / metabolism Tauopathies / diagnostic imaging Aged Female Male Aged, 80 and over Middle Aged Brain / metabolism

Journal

Science translational medicine
ISSN: 1946-6242
Titre abrégé: Sci Transl Med
Pays: United States
ID NLM: 101505086

Informations de publication

Date de publication:
24 Jul 2024
Historique:
medline: 26 7 2024
pubmed: 26 7 2024
entrez: 24 7 2024
Statut: ppublish

Résumé

[

Identifiants

DOI: 10.1126/scitranslmed.ado8076 PMID: 39047115
pubmed: 39047115
doi: 10.1126/scitranslmed.ado8076
doi:

Substances chimiques

tau Proteins 0
Carbolines 0
Amyloid beta-Peptides 0
7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole J09QS3Z3WB

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

eado8076

Auteurs

Keith A Josephs (KA)

Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA.
ORCID: 0000-0003-2930-8634

Nirubol Tosakulwong (N)

Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN 55905, USA.
ORCID: 0000-0002-2385-6835

Stephen D Weigand (SD)

Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN 55905, USA.

Jonathan Graff-Radford (J)

Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA.

Christopher G Schwarz (CG)

Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA.
ORCID: 0000-0002-1466-8357

Matthew L Senjem (ML)

Department of Information Technology, Mayo Clinic, Rochester, MN 55905, USA.
ORCID: 0000-0001-9308-9275

Mary M Machulda (MM)

Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA.
ORCID: 0000-0003-4834-5967

Kejal Kantarci (K)

Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA.
ORCID: 0000-0002-8001-2081

David S Knopman (DS)

Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA.
ORCID: 0000-0002-6544-066X

Aivi Nguyen (A)

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA.
ORCID: 0000-0003-1809-9451

R Ross Reichard (RR)

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA.

Dennis W Dickson (DW)

Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.
ORCID: 0000-0001-7189-7917

Ronald C Petersen (RC)

Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA.
ORCID: 0000-0002-8178-6601

Val J Lowe (VJ)

Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA.

Clifford R Jack (CR)

Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA.
ORCID: 0000-0001-7916-622X

Jennifer L Whitwell (JL)

Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Flortaucipir PET uncovers relationships...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic radioisotopique › Scintigraphie › Tomoscintigraphie › Tomographie par émission de positons › Flortaucipir PET uncovers relationships...
questionsmedicales.fr › Troubles mentaux › Troubles neurocognitifs › Démence › Maladie d'Alzheimer › Flortaucipir PET uncovers relationships...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de tissu nerveux › Protéines associées aux microtubules › Protéines tau › Flortaucipir PET uncovers relationships...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérocycliques 3 noyaux › Carbolines › Flortaucipir PET uncovers relationships...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Peptides bêta-amyloïdes › Flortaucipir PET uncovers relationships...
questionsmedicales.fr › Maladies du système nerveux › Maladies neurodégénératives › Tauopathies › Flortaucipir PET uncovers relationships...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Flortaucipir PET uncovers relationships...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Sujet âgé de 80 ans ou plus › Flortaucipir PET uncovers relationships...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › Flortaucipir PET uncovers relationships...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Flortaucipir PET uncovers relationships...