SLC25A48 influences plasma levels of choline and localizes to the inner mitochondrial membrane.
Betaine
Choline
Inner mitochondrial membrane transport
Mitochondria
One carbon metabolism
SLC25A48
Journal
Molecular genetics and metabolism
ISSN: 1096-7206
Titre abrégé: Mol Genet Metab
Pays: United States
ID NLM: 9805456
Informations de publication
Date de publication:
20 Jun 2024
20 Jun 2024
Historique:
received:
28
03
2024
revised:
14
06
2024
accepted:
17
06
2024
medline:
26
7
2024
pubmed:
26
7
2024
entrez:
24
7
2024
Statut:
aheadofprint
Résumé
Choline contributes to the biogenesis of methyl groups, neurotransmitters, and cell membranes. Our genome-wide association study (GWAS) of circulating choline in 2228 college students found that alleles in SLC25A48 (rs6596270) influence choline concentrations in men (p = 9.6 × 10
Identifiants
pubmed: 39047301
pii: S1096-7192(24)00402-5
doi: 10.1016/j.ymgme.2024.108518
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
108518Informations de copyright
Copyright © 2024. Published by Elsevier Inc.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors have no competing interests to declare.