Pepsinogen I, pepsinogen II, gastrin-17, and

Helicobacter pylori atrophic gastritis biomarkers gastric cancer intestinal metaplasia

Journal

Archives of medical science : AMS
ISSN: 1734-1922
Titre abrégé: Arch Med Sci
Pays: Poland
ID NLM: 101258257

Informations de publication

Date de publication:
2024
Historique:
received: 16 01 2024
accepted: 12 06 2024
medline: 26 7 2024
pubmed: 26 7 2024
entrez: 25 7 2024
Statut: epublish

Résumé

Atrophic gastritis and intestinal metaplasia are precursor lesions of gastric cancer. The aim of this study was to determine the usefulness of the biomarkers pepsinogen I(PgI), pepsinogen II (PgII), gastrin-17, and We studied 129 patients with gastric symptoms. The biomarker status was determined using GastroPanel by means of the ELISA-technique. Biomarkers detected atrophy in 14% of the subjects, and 49.6% had positive antibodies for In the Western Mexican population, precursor lesions (AG, IM) are common in adults (45%) with dyspepsia but infrequent in children (8%).

Identifiants

pubmed: 39050166
doi: 10.5114/aoms/189971
pii: 189971
pmc: PMC11264142
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1016-1021

Informations de copyright

Copyright: © 2024 Termedia & Banach.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

Références

Exp Ther Med. 2021 Nov;22(5):1347
pubmed: 34630701
Arch Med Sci. 2019 Oct;15(6):1475-1481
pubmed: 31749876
Transl Gastroenterol Hepatol. 2022 Jan 25;7:8
pubmed: 35243117
Eur J Cancer Prev. 2023 Sep 1;32(5):478-484
pubmed: 36912185
Rev Gastroenterol Peru. 2012 Jan-Mar;32(1):50-7
pubmed: 22476178
Am J Surg Pathol. 2015 Jun;39(6):786-92
pubmed: 25602795
Dig Dis Sci. 2014 Aug;59(8):1698-709
pubmed: 24563236
Helicobacter. 2007 Aug;12(4):354-8
pubmed: 17669109
J Clin Pathol. 2005 Nov;58(11):1189-93
pubmed: 16254110
Arq Gastroenterol. 2021 Jan-Mar;58(1):39-47
pubmed: 33909795
Gut. 1999 May;44(5):693-7
pubmed: 10205207
Arq Gastroenterol. 2020 Apr-Jun;57(2):154-160
pubmed: 32609157
Cancer. 1993 Jan 15;71(2):297-301
pubmed: 8422620

Auteurs

Josefina Yoaly Sánchez-López (JY)

División de Genética, Centro de Investigación Biomédica de Occidente, Instituto Mexicano del Seguro Social, Mexico.

Luis Carlos Díaz-Herrera (LC)

Servicio de Gastroenterología, Hospital de Especialidades, Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social, Mexico.

Lourdes Del Carmen Rizo-de la Torre (LDC)

División de Medicina Molecular, Centro de Investigación Biomédica de Occidente, Instituto Mexicano del Seguro Social, Mexico.

Classifications MeSH