Efficacy of statin therapy in reducing epicardial adipose tissue: a systematic review and meta-analysis.
cardiovascular disease
coronary artery disease
epicardial adipose tissue
statin
systematic review
Journal
Archives of medical science : AMS
ISSN: 1734-1922
Titre abrégé: Arch Med Sci
Pays: Poland
ID NLM: 101258257
Informations de publication
Date de publication:
2024
2024
Historique:
received:
24
05
2024
accepted:
03
06
2024
medline:
26
7
2024
pubmed:
26
7
2024
entrez:
25
7
2024
Statut:
epublish
Résumé
Understanding the effect of statins on epicardial adipose tissue (EAT) is important as it may help reduce the negative impact of EAT-derived molecules on the cardiovascular system and consequently on coronary artery disease. Thus, we aimed to perform a systematic review and meta-analysis to assess the impact of statin therapy on EAT. The study utilized Scopus, PubMed, Embase, and Web of Science to gather relevant studies on the impacts of statins on EAT until September 5 In the meta-analysis, three studies involving 512 subjects were ultimately incorporated. The findings indicated a significant decrease in EAT after treatment with statins (standardized mean difference (SMD = -0.507, 95% CI: -2.536, 1.521, Statins appear to exert an additional cardiovascular therapeutic effect by reducing EAT.
Identifiants
pubmed: 39050169
doi: 10.5114/aoms/189575
pii: 189575
pmc: PMC11264093
doi:
Types de publication
Journal Article
Langues
eng
Pagination
997-1001Informations de copyright
Copyright: © 2024 Termedia & Banach.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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