Mepitel film for the prevention of radiation dermatitis: A comprehensive review of its efficacy, side effects, physics measurements, patient- and clinician-reported outcomes.
Acute radiation dermatitis
Acute skin toxicity
Cancer
Mepitel film
Patient-reported outcomes
Journal
Asia-Pacific journal of oncology nursing
ISSN: 2347-5625
Titre abrégé: Asia Pac J Oncol Nurs
Pays: United States
ID NLM: 101673157
Informations de publication
Date de publication:
Aug 2024
Aug 2024
Historique:
received:
24
04
2024
accepted:
29
05
2024
medline:
26
7
2024
pubmed:
26
7
2024
entrez:
25
7
2024
Statut:
epublish
Résumé
This review aimed to summarize the benefits, side effects, physics measurements, and patient- and clinician-reported outcomes of Mepitel film (MF) in preventing radiation dermatitis (RD) for cancer patients. The online database PubMed was searched from inception to April 15, 2024 with the search terms "Mepitel film" or "Mepitel." Articles of any study design evaluating MF for the prevention of RD were included. Non-human studies were excluded. The database search identified 119 articles and 13 of them were included in this review. Across these studies, MF was found to be beneficial in reducing RD and improved patient- and clinician-reported outcomes in breast and head and neck cancers. Side effects of MF included itchiness, acne, allergic reaction, tightness, discomfort, and poor film adherence, but patient dropouts were uncommon. MF did not cause a bolus effect or increased skin dose in physics measurements. MF is a safe and effective intervention for preventing acute RD. It should be recommended in breast cancer patients where the data is more robust. Further research is needed to evaluate MF's efficacy on patients with different skin tones, its cost-effectiveness, and identifying patients who most benefit from MF relative to other effective interventions.
Identifiants
pubmed: 39051046
doi: 10.1016/j.apjon.2024.100530
pii: S2347-5625(24)00152-5
pmc: PMC11268185
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
100530Informations de copyright
© 2024 The Author(s).
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