Photon counting CT clinical adoption, integration, and workflow.
Photon Counting CT
Photon counting detector CT
Photon counting workflow
Journal
Abdominal radiology (New York)
ISSN: 2366-0058
Titre abrégé: Abdom Radiol (NY)
Pays: United States
ID NLM: 101674571
Informations de publication
Date de publication:
25 Jul 2024
25 Jul 2024
Historique:
received:
01
03
2024
accepted:
16
07
2024
revised:
15
07
2024
medline:
26
7
2024
pubmed:
26
7
2024
entrez:
25
7
2024
Statut:
aheadofprint
Résumé
Photon counting CT was recently introduced into clinical practice [Rajendran K, Petersilka M, Henning A, Shanblatt ER, Schmidt B, Flohr TG, Ferrero A, Baffour F, Diehn FE, Yu L, Rajiah P, Fletcher JG, Leng S, McCollough CH. First Clinical Photon-counting Detector CT System: Technical Evaluation. Radiology 2022;303(1):130-138. doi: https://doi.org/10.1148/radiol.212579 ]. Photon counting detectors (PCD) afford better spatial resolution, radiation dose efficiency, and iodine contrast-to-noise than EID-CT [Leng S, Bruesewitz M, Tao S, Rajendran K, Halaweish AF, Campeau NG, Fletcher JG, McCollough CH. Photon-counting Detector CT: System Design and Clinical Applications of an Emerging Technology. Radiographics 2019;39(3):729-743. doi: https://doi.org/10.1148/rg.2019180115 ); (Leng S, Rajendran K, Gong H, Zhou W, Halaweish AF, Henning A, Kappler S, Baer M, Fletcher JG, McCollough CH. 150-mum Spatial Resolution Using Photon-Counting Detector Computed Tomography Technology: Technical Performance and First Patient Images. Invest Radiol 2018;53(11):655-662. doi: https://doi.org/10.1097/RLI.0000000000000488 )(Booij R, van der Werf NR, Dijkshoorn ML, van der Lugt A, van Straten M. Assessment of Iodine Contrast-To-Noise Ratio in Virtual Monoenergetic Images Reconstructed from Dual-Source Energy-Integrating CT and Photon-Counting CT Data. Diagnostics (Basel) 2022;12(6). doi: https://doi.org/10.3390/diagnostics12061467 ); (Sawall S, Klein L, Amato C, Wehrse E, Dorn S, Maier J, Heinze S, Schlemmer HP, Ziener CH, Uhrig M, Kachelriess M. Iodine contrast-to-noise ratio improvement at unit dose and contrast media volume reduction in whole-body photon-counting CT. Eur J Radiol 2020;126:108909. doi: https://doi.org/10.1016/j.ejrad.2020.108909 ] while also maintaining multienergy CT (MECT) capabilities[Flohr T, Petersilka M, Henning A, Ulzheimer S, Ferda J, Schmidt B. Photon-counting CT review. Phys Med 2020;79:126-136. doi: https://doi.org/10.1016/j.ejmp.2020.10.030 ]. This article will review the clinical adoption of PCD-CT including protocol development, clinical applications, clinical integration and workflow considerations. Protocol development is institution specific and involves collaborative decision-making among radiologists, physicists, and technologists. Key PCD clinical applications include radiation exposure reduction, intravenous contrast volume reduction, and improved lesion conspicuity. Patients who would most benefit from these improvements may preferentially be scanned with PCD CT. With numerous available reconstructions, radiologists should be strategic in the series sent to PACS for interpretation and routinely sending spectral series to PACS can facilitate integration with clinical workflow. The Society of Abdominal Radiology PCD Emerging Technology Commission endorsed this article.
Identifiants
pubmed: 39052057
doi: 10.1007/s00261-024-04503-5
pii: 10.1007/s00261-024-04503-5
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
Références
Rajendran K, Petersilka M, Henning A, Shanblatt ER, Schmidt B, Flohr TG, Ferrero A, Baffour F, Diehn FE, Yu L, Rajiah P, Fletcher JG, Leng S, McCollough CH. First Clinical Photon-counting Detector CT System: Technical Evaluation. Radiology 2022;303(1):130–138. doi: https://doi.org/10.1148/radiol.212579
doi: 10.1148/radiol.212579
pubmed: 34904876
Leng S, Bruesewitz M, Tao S, Rajendran K, Halaweish AF, Campeau NG, Fletcher JG, McCollough CH. Photon-counting Detector CT: System Design and Clinical Applications of an Emerging Technology. Radiographics 2019;39(3):729–743. doi: https://doi.org/10.1148/rg.2019180115
doi: 10.1148/rg.2019180115
pubmed: 31059394
Leng S, Rajendran K, Gong H, Zhou W, Halaweish AF, Henning A, Kappler S, Baer M, Fletcher JG, McCollough CH. 150-mum Spatial Resolution Using Photon-Counting Detector Computed Tomography Technology: Technical Performance and First Patient Images. Invest Radiol 2018;53(11):655–662. doi: https://doi.org/10.1097/RLI.0000000000000488
doi: 10.1097/RLI.0000000000000488
pubmed: 29847412
pmcid: 6173631
Booij R, van der Werf NR, Dijkshoorn ML, van der Lugt A, van Straten M. Assessment of Iodine Contrast-To-Noise Ratio in Virtual Monoenergetic Images Reconstructed from Dual-Source Energy-Integrating CT and Photon-Counting CT Data. Diagnostics (Basel) 2022;12(6). doi: https://doi.org/10.3390/diagnostics12061467
Sawall S, Klein L, Amato C, Wehrse E, Dorn S, Maier J, Heinze S, Schlemmer HP, Ziener CH, Uhrig M, Kachelriess M. Iodine contrast-to-noise ratio improvement at unit dose and contrast media volume reduction in whole-body photon-counting CT. Eur J Radiol 2020;126:108909. doi: https://doi.org/10.1016/j.ejrad.2020.108909
doi: 10.1016/j.ejrad.2020.108909
pubmed: 32145600
Flohr T, Petersilka M, Henning A, Ulzheimer S, Ferda J, Schmidt B. Photon-counting CT review. Phys Med 2020;79:126–136. doi: https://doi.org/10.1016/j.ejmp.2020.10.030
doi: 10.1016/j.ejmp.2020.10.030
pubmed: 33249223
Willemink MJ, Persson M, Pourmorteza A, Pelc NJ, Fleischmann D. Photon-counting CT: Technical Principles and Clinical Prospects. Radiology 2018;289(2):293–312. doi: https://doi.org/10.1148/radiol.2018172656
doi: 10.1148/radiol.2018172656
pubmed: 30179101
McCollough CH, Rajendran K, Leng S, Yu L, Fletcher JG, Stierstorfer K, Flohr TG. The technical development of photon-counting detector CT. Eur Radiol 2023;33(8):5321–5330. doi: https://doi.org/10.1007/s00330-023-09545-9
doi: 10.1007/s00330-023-09545-9
pubmed: 37014409
Esquivel A, Ferrero A, Mileto A, Baffour F, Horst K, Rajiah PS, Inoue A, Leng S, McCollough C, Fletcher JG. Photon-Counting Detector CT: Key Points Radiologists Should Know. Korean J Radiol 2022;23(9):854–865. doi: https://doi.org/10.3348/kjr.2022.0377
doi: 10.3348/kjr.2022.0377
pubmed: 36047540
pmcid: 9434736
McCollough CH, Rajendran K, Baffour FI, Diehn FE, Ferrero A, Glazebrook KN, Horst KK, Johnson TF, Leng S, Mileto A, Rajiah PS, Schmidt B, Yu L, Flohr TG, Fletcher JG. Clinical applications of photon counting detector CT. Eur Radiol 2023;33(8):5309–5320. doi: https://doi.org/10.1007/s00330-023-09596-y
doi: 10.1007/s00330-023-09596-y
pubmed: 37020069
Yalon M, Inoue A, Thorne JE, Lee YS, Johnson MP, Esquivel A, Leng S, McCollough CH, Fletcher JG, Rajiah PS. Infrapopliteal Segments on Lower-Extremity CTA: Prospective Intraindividual Comparison of Energy-Integrating Detector CT and Photon-Counting Detector CT. AJR Am J Roentgenol 2023. doi: https://doi.org/10.2214/AJR.23.29778
doi: 10.2214/AJR.23.29778
pubmed: 37991334
Mazzei MA, Khader L, Cirigliano A, Cioffi Squitieri N, Guerrini S, Forzoni B, Marrelli D, Roviello F, Mazzei FG, Volterrani L. Accuracy of MDCT in the preoperative definition of Peritoneal Cancer Index (PCI) in patients with advanced ovarian cancer who underwent peritonectomy and hyperthermic intraperitoneal chemotherapy (HIPEC). Abdom Imaging 2013;38(6):1422–1430. doi: https://doi.org/10.1007/s00261-013-0013-9
doi: 10.1007/s00261-013-0013-9
pubmed: 23744439
Cao J, Bache S, Schwartz FR, Frush D. Pediatric Applications of Photon-Counting Detector CT. AJR Am J Roentgenol 2023;220(4):580–589. doi: https://doi.org/10.2214/AJR.22.28391
doi: 10.2214/AJR.22.28391
pubmed: 36287620
Hagen F, Hofmann J, Wrazidlo R, Gutjahr R, Schmidt B, Faby S, Nikolaou K, Horger M. Image quality and dose exposure of contrast-enhanced abdominal CT on a 1st generation clinical dual-source photon-counting detector CT in obese patients vs. a 2nd generation dual-source dual energy integrating detector CT. Eur J Radiol 2022;151:110325. doi: https://doi.org/10.1016/j.ejrad.2022.110325
doi: 10.1016/j.ejrad.2022.110325
pubmed: 35472649
Higashigaito K, Mergen V, Eberhard M, Jungblut L, Hebeisen M, Ratzer S, Zanini B, Kobe A, Martini K, Euler A, Alkadhi H. CT Angiography of the Aorta Using Photon-counting Detector CT with Reduced Contrast Media Volume. Radiol Cardiothorac Imaging 2023;5(1):e220140. doi: https://doi.org/10.1148/ryct.220140
doi: 10.1148/ryct.220140
pubmed: 36860835
pmcid: 9969214
Dekker HM, Stroomberg GJ, Prokop M. Tackling the increasing contamination of the water supply by iodinated contrast media. Insights Imaging 2022;13(1):30. doi: https://doi.org/10.1186/s13244-022-01175-x
doi: 10.1186/s13244-022-01175-x
pubmed: 35201493
pmcid: 8873335
Kim J, Mabud T, Huang C, Lloret Del Hoyo J, Petrocelli R, Vij A, Dane B. Inter-reader agreement of pancreatic adenocarcinoma resectability assessment with photon counting versus energy integrating detector CT. Abdom Radiol (NY) 2024. doi: https://doi.org/10.1007/s00261-024-04298-5
doi: 10.1007/s00261-024-04298-5
pubmed: 38976054
Dane B, Kim J, Qian K, Megibow A. Pancreatic cyst prevalence and detection with photon counting CT compared with conventional energy integrating detector CT. Eur J Radiol 2024;175:111437. doi: https://doi.org/10.1016/j.ejrad.2024.111437
doi: 10.1016/j.ejrad.2024.111437
pubmed: 38520805
Dane B, Ruff A, O’Donnell T, El-Ali A, Ginocchio L, Prabhu V, Megibow A. Photon-Counting Computed Tomography Versus Energy-Integrating Dual-Energy Computed Tomography: Virtual Noncontrast Image Quality Comparison. J Comput Assist Tomogr 2023. doi: https://doi.org/10.1097/RCT.0000000000001562
doi: 10.1097/RCT.0000000000001562
pubmed: 38013203
Sartoretti T, Mergen V, Higashigaito K, Eberhard M, Alkadhi H, Euler A. Virtual Noncontrast Imaging of the Liver Using Photon-Counting Detector Computed Tomography: A Systematic Phantom and Patient Study. Invest Radiol 2022;57(7):488–493. doi: https://doi.org/10.1097/RLI.0000000000000860
doi: 10.1097/RLI.0000000000000860
pubmed: 35136003
Dane B, Freedman D, Qian K, Ginocchio L, Smereka P, Megibow A. Photon-counting CT urogram: optimal acquisition potential (kV) determination for virtual noncontrast creation. Abdom Radiol (NY) 2023. doi: https://doi.org/10.1007/s00261-023-04113-7
doi: 10.1007/s00261-023-04113-7
pubmed: 38006415
Bette S, Risch F, Canalini L, Becker J, Leithner EV, Huber A, Haerting M, Jehs B, Wollny C, Schwarz F, Tehlan K, Scheurig-Muenkler C, Wendler T, Kroencke T, Decker JA. Diagnostic performance of photon-counting detector CT for differentiation between adrenal adenomas and metastases. Eur Radiol 2024. doi: https://doi.org/10.1007/s00330-024-10675-x
doi: 10.1007/s00330-024-10675-x
pubmed: 38480567
Rau S, Rau A, Stein T, Hagar MT, Faby S, Bamberg F, Weiss J. Value of virtual non-contrast images to identify uncomplicated cystic renal lesions: photon-counting detector CT vs. dual-energy integrating detector CT. Radiol Med 2024;129(5):669–676. doi: https://doi.org/10.1007/s11547-024-01801-2
doi: 10.1007/s11547-024-01801-2
pubmed: 38512614
pmcid: 11088563
Dane B, Qian K, Soni R, Megibow A. Crohn’s disease inflammation severity assessment with iodine density from photon counting CT enterography: comparison with endoscopic histopathology. Abdom Radiol (NY) 2023. doi: https://doi.org/10.1007/s00261-023-04060-3
doi: 10.1007/s00261-023-04060-3
pubmed: 38006415
Mileto A, Ananthakrishnan L, Morgan DE, Yeh BM, Marin D, Kambadakone AR. Clinical Implementation of Dual-Energy CT for Gastrointestinal Imaging. AJR Am J Roentgenol 2021;217(3):651–663. doi: https://doi.org/10.2214/AJR.20.25093
doi: 10.2214/AJR.20.25093
pubmed: 33377415
Megibow AJ, Kambadakone A, Ananthakrishnan L. Dual-Energy Computed Tomography: Image Acquisition, Processing, and Workflow. Radiol Clin North Am 2018;56(4):507–520. doi: https://doi.org/10.1016/j.rcl.2018.03.001
doi: 10.1016/j.rcl.2018.03.001
pubmed: 29936944
Bette S, Decker JA, Braun FM, Becker J, Haerting M, Haeckel T, Gebhard M, Risch F, Woznicki P, Scheurig-Muenkler C, Kroencke TJ, Schwarz F. Optimal Conspicuity of Liver Metastases in Virtual Monochromatic Imaging Reconstructions on a Novel Photon-Counting Detector CT-Effect of keV Settings and BMI. Diagnostics (Basel) 2022;12(5). doi: https://doi.org/10.3390/diagnostics12051231
Wrazidlo R, Walder L, Estler A, Gutjahr R, Schmidt B, Faby S, Fritz J, Nikolaou K, Horger M, Hagen F. Radiation Dose Reduction in Contrast-Enhanced Abdominal CT: Comparison of Photon-Counting Detector CT with 2nd Generation Dual-Source Dual-Energy CT in an oncologic cohort. Acad Radiol 2023;30(5):855–862. doi: https://doi.org/10.1016/j.acra.2022.05.021
doi: 10.1016/j.acra.2022.05.021
pubmed: 35760710
Madhavan AA, Yu L, Brinjikji W, Cutsforth-Gregory JK, Schwartz FR, Mark IT, Benson JC, Amrhein TJ. Utility of Photon-Counting Detector CT Myelography for the Detection of CSF-Venous Fistulas. AJNR Am J Neuroradiol 2023;44(6):740–744. doi: https://doi.org/10.3174/ajnr.A7887
doi: 10.3174/ajnr.A7887
pubmed: 37202116
pmcid: 10249691
Rajagopal JR, Schwartz FR, Solomon JB, Enterline DS, Samei E. High Spatial-Resolution Skull Base Imaging With Photon-Counting Computed Tomography and Energy-Integrating Computed Tomography: A Comparative Phantom Study. J Comput Assist Tomogr 2023;47(4):613–620. doi: https://doi.org/10.1097/RCT.0000000000001464
doi: 10.1097/RCT.0000000000001464
pubmed: 37380149
pmcid: 10356746
Atwi NE, Sabottke CF, Pitre DM, Smith DL, Danrad R, Dharaiya E, Kambadakone A, Pandharipande PV, Toshav AM. Follow-up Recommendation Rates Associated With Spectral Detector Dual-Energy CT of the Abdomen and Pelvis: A Retrospective Comparison to Single-Energy CT. J Am Coll Radiol 2020;17(7):940–950. doi: https://doi.org/10.1016/j.jacr.2019.12.029
doi: 10.1016/j.jacr.2019.12.029
pubmed: 32032553
Mileto A, Sofue K, Marin D. Imaging the renal lesion with dual-energy multidetector CT and multi-energy applications in clinical practice: what can it truly do for you? Eur Radiol 2016;26(10):3677–3690. doi: https://doi.org/10.1007/s00330-015-4180-7
doi: 10.1007/s00330-015-4180-7
pubmed: 26801162
Shuman WP, Green DE, Busey JM, Mitsumori LM, Choi E, Koprowicz KM, Kanal KM. Dual-energy liver CT: effect of monochromatic imaging on lesion detection, conspicuity, and contrast-to-noise ratio of hypervascular lesions on late arterial phase. AJR Am J Roentgenol 2014;203(3):601–606. doi: https://doi.org/10.2214/AJR.13.11337
doi: 10.2214/AJR.13.11337
pubmed: 25148163
Voss BA, Khandelwal A, Wells ML, Inoue A, Venkatesh SK, Lee YS, Johnson MP, Fletcher JG. Impact of dual-energy 50-keV virtual monoenergetic images on radiologist confidence in detection of key imaging findings of small hepatocellular carcinomas using multiphase liver CT. Acta Radiol 2022;63(11):1443–1452. doi: https://doi.org/10.1177/02841851211052993
doi: 10.1177/02841851211052993
pubmed: 34723681
Decker JA, Bette S, Lubina N, Rippel K, Braun F, Risch F, Woznicki P, Wollny C, Scheurig-Muenkler C, Kroencke TJ, Schwarz F. Low-dose CT of the abdomen: Initial experience on a novel photon-counting detector CT and comparison with energy-integrating detector CT. Eur J Radiol 2022;148:110181. doi: https://doi.org/10.1016/j.ejrad.2022.110181
doi: 10.1016/j.ejrad.2022.110181
pubmed: 35121331
Andersen MB, Ebbesen D, Thygesen J, Kruis M, Rasmussen F. Impact of spectral body imaging in patients suspected for occult cancer: a prospective study of 503 patients. Eur Radiol 2020;30(10):5539–5550. doi: https://doi.org/10.1007/s00330-020-06878-7
doi: 10.1007/s00330-020-06878-7
pubmed: 32367416
pmcid: 7476920