A Short Progressive Supranuclear Palsy Quality of Life Scale.

PSP Quality of Life scale health‐related quality of life progressive supranuclear palsy rating scale

Journal

Movement disorders : official journal of the Movement Disorder Society
ISSN: 1531-8257
Titre abrégé: Mov Disord
Pays: United States
ID NLM: 8610688

Informations de publication

Date de publication:
26 Jul 2024
Historique:
revised: 27 05 2024
received: 20 03 2024
accepted: 13 06 2024
medline: 26 7 2024
pubmed: 26 7 2024
entrez: 26 7 2024
Statut: aheadofprint

Résumé

The Progressive Supranuclear Palsy quality of life scale (PSP-QoL) has been shown to be a useful tool for capturing health-related quality of life of patients in "everyday life" and in progressive supranuclear palsy (PSP) research. However, at 45 items in length, the questionnaire can take a long time, exhausting PSP patients, in particular if cognitive impaired, which can have a negative impact on the assessment. The aim of this study was to establish a condensed version of the PSP-QoL for research and routine clinical care. In this retrospective study, data originating from a German cohort of PSP patients was analyzed. Data from 245 PSP patients were included in this study. The short PSP-QoL questionnaire was created using a two-factor solution and item-total and inter-item correlations for mental and physical aspects of daily living of the PSP-QoL followed by confirmatory factor analysis. The final scale included 12 items representing mental (five items) and physical symptoms (seven items). The specified two-factor model displayed an excellent fit in the confirmatory factor analysis. The short Progressive Supranuclear Palsy Quality of Life scale (PSP-ShoQoL) correlated moderately with the PSP Rating Scale (r [243] = 0.514, P < 0.001) and Geriatric depression scale (r [231] = 0.548, P < 0.001). Sensitivity to change confirmed a significant decrease in QoL after 12 months. In this study, we created a 12-item PSP-ShoQoL designed to "facilitate" daily clinical work that correlated strongly with the PSP-QoL and was sensitive to change. © 2024 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

Identifiants

pubmed: 39056204
doi: 10.1002/mds.29936
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

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Auteurs

Ida Jensen (I)

Department of Neurology, Hannover Medical School, Hannover, Germany.
Department of Neurology, LMU University Hospital, Munich, Germany.

Stephanie Stiel (S)

Institute for General Practice and Palliative Care, Hannover Medical School, Hannover, Germany.

Sarah Bebermeier (S)

Department of Pedagogic Psychology, Leibniz University Hannover, Hannover, Germany.

Anette Schrag (A)

Department of Clinical and Movement Neurosciences, Queen Square Institute of Neurology, London, United Kingdom.

Stephan Greten (S)

Department of Neurology, Hannover Medical School, Hannover, Germany.

Johanna Doll-Lee (J)

Department of Neurology, Hannover Medical School, Hannover, Germany.

Florian Wegner (F)

Department of Neurology, Hannover Medical School, Hannover, Germany.

Lan Ye (L)

Department of Neurology, Hannover Medical School, Hannover, Germany.

Johanne Heine (J)

Department of Neurology, Hannover Medical School, Hannover, Germany.

Lea Krey (L)

Department of Neurology, Hannover Medical School, Hannover, Germany.

Matthias Höllerhage (M)

Department of Neurology, Hannover Medical School, Hannover, Germany.

Patrick Süß (P)

Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Center of Rare Diseases Erlangen (ZSEER), University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

Jürgen Winkler (J)

Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Center of Rare Diseases Erlangen (ZSEER), University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

Daniela Berg (D)

Department of Neurology, Kiel University, Kiel, Germany.

Steffen Paschen (S)

Department of Neurology, Kiel University, Kiel, Germany.

Lars Tönges (L)

Department of Neurology, St. Josef-Hospital, Ruhr University Bochum, Bochum, Germany.
Neurodegeneration Research, Protein Research Unit Ruhr (PURE), Ruhr University Bochum, Bochum, Germany.

Doreen Gruber (D)

Movement Disorders Hospital, Beelitz-Heilstätten, Beelitz-Heilstätten, Germany.
Department of Neurology, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.

Florin Gandor (F)

Movement Disorders Hospital, Beelitz-Heilstätten, Beelitz-Heilstätten, Germany.
Department of Neurology, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.

Wolfgang H Jost (WH)

Parkinson-Klinik Ortenau, Wolfach, Germany.

Andrea A Kühn (AA)

Movement Disorder and Neuromodulation Unit, Department of Neurology, Charité, University Medicine Berlin, Berlin, Germany.
German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.

Inga Claus (I)

Department of Neurology with Institute of Translational Neurology, University Hospital Muenster, Muenster, Germany.

Tobias Warnecke (T)

Department of Neurology and Neurorehabilitation, Klinikum Osnabrueck-Academic teaching hospital of the WWU Muenster, Osnabrueck, Germany.

David J Pedrosa (DJ)

Department of Neurology, University Hospital of Marburg, Marburg, Germany.

Carsten Eggers (C)

Department of Neurology, Knappschaftskrankenhaus Bottrop, Bottrop, Germany.

Claudia Trenkwalder (C)

Paracelsus-Elena Klinik, Kassel, Germany.

Joseph Classen (J)

Department of Neurology, University of Leipzig Medical Center, Leipzig, Germany.

Johannes Schwarz (J)

Department of Neurology, Klinik Haag I. OB, Mühldorf a. Inn, Germany.

Monika Pötter-Nerger (M)

Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Jan Kassubek (J)

Department of Neurology, University of Ulm, Ulm, Germany.
German Center for Neurodegenerative Diseases (DZNE), Oberer Eselsberg, Ulm, Germany.

Alfons Schnitzler (A)

Institute of Clinical Neuroscience and Medical Psychology, and Department of Neurology, University of Düsseldorf, Düsseldorf, Germany.

Günter U Höglinger (GU)

Department of Neurology, LMU University Hospital, Munich, Germany.
Munich Cluster for Systems Neurology (SyNergy) Munich, Munich, Germany.

Martin Klietz (M)

Department of Neurology, Hannover Medical School, Hannover, Germany.

Classifications MeSH