Impact of Obstructive Sleep Apnea and Sympathetic Nervous System on Cardiac Health: A Comprehensive Review.

cardiac risk cardiovascular health sleep apnea sympathetic activation sympathetic nervous system

Journal

Journal of cardiovascular development and disease
ISSN: 2308-3425
Titre abrégé: J Cardiovasc Dev Dis
Pays: Switzerland
ID NLM: 101651414

Informations de publication

Date de publication:
30 Jun 2024
Historique:
received: 28 05 2024
revised: 22 06 2024
accepted: 26 06 2024
medline: 26 7 2024
pubmed: 26 7 2024
entrez: 26 7 2024
Statut: epublish

Résumé

A prevalent condition linked to an elevated risk of cardiovascular disease is sleep apnea. This review examines the connections between cardiac risk, the sympathetic nervous system, and sleep apnea. The increased risk of hypertension, arrhythmias, myocardial infarction, and heart failure was highlighted in the pathophysiology of sleep apnea and its effect on sympathetic activation. It is also important to consider potential processes such as oxidative stress, inflammation, endothelial dysfunction, and autonomic imbalance that may relate sleep apnea-induced sympathetic activation to cardiac risk. With implications for creating innovative diagnostic and treatment approaches to lessen the cardiovascular effects of sleep apnea, the goal of this investigation is to improve the understanding of the intricate link between sympathetic activity, cardiac risk, and sleep apnea. This study aimed to clarify the complex relationship between cardiovascular health and sleep apnea by synthesizing the available research and highlighting the crucial role played by the sympathetic nervous system in moderating this relationship. Our thorough investigation may have important therapeutic ramifications that will direct the creation of focused therapies to enhance cardiovascular outcomes in sleep apnea sufferers.

Identifiants

pubmed: 39057624
pii: jcdd11070204
doi: 10.3390/jcdd11070204
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Auteurs

Antonino Maniaci (A)

Department of Medicine and Surgery, University of Enna "Kore", 94100 Enna, Italy.

Salvatore Lavalle (S)

Department of Medicine and Surgery, University of Enna "Kore", 94100 Enna, Italy.

Federica Maria Parisi (FM)

Department of Medical, Surgical Sciences and Advanced Technologies "GF Ingrassia" ENT Section, University of Catania, 95123 Catania, Italy.

Marco Barbanti (M)

Department of Medicine and Surgery, University of Enna "Kore", 94100 Enna, Italy.

Salvatore Cocuzza (S)

Department of Medical, Surgical Sciences and Advanced Technologies "GF Ingrassia" ENT Section, University of Catania, 95123 Catania, Italy.

Giannicola Iannella (G)

Otorhinolaryngology Department, Sapienza University of Rome, Policlinico Umberto I, Viale del Policlinico, 00161 Rome, Italy.

Giuseppe Magliulo (G)

Otorhinolaryngology Department, Sapienza University of Rome, Policlinico Umberto I, Viale del Policlinico, 00161 Rome, Italy.

Annalisa Pace (A)

Otorhinolaryngology Department, Sapienza University of Rome, Policlinico Umberto I, Viale del Policlinico, 00161 Rome, Italy.

Mario Lentini (M)

ASP Ragusa-Hospital Giovanni Paolo II, 97100 Ragusa, Italy.

Edoardo Masiello (E)

Radiology Unit, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, 20132 Milan, Italy.

Luigi La Via (L)

Department of Anesthesia and Intensive Care, Azienda Ospedaliero Universitaria Policlinico "G. Rodolico-San Marco", 95123 Catania, Italy.

Classifications MeSH