Residual Kidney Function in Hemodialysis: Its Importance and Contribution to Improved Patient Outcomes.

incremental hemodialysis randomized controlled trial residual kidney function

Journal

Toxins
ISSN: 2072-6651
Titre abrégé: Toxins (Basel)
Pays: Switzerland
ID NLM: 101530765

Informations de publication

Date de publication:
28 Jun 2024
Historique:
received: 30 04 2024
revised: 27 05 2024
accepted: 11 06 2024
medline: 26 7 2024
pubmed: 26 7 2024
entrez: 26 7 2024
Statut: epublish

Résumé

Individuals afflicted with advanced kidney dysfunction who require dialysis for medical management exhibit different degrees of native kidney function, called residual kidney function (RKF), ranging from nil to appreciable levels. The primary focus of this manuscript is to delve into the concept of RKF, a pivotal yet under-represented topic in nephrology. To begin, we unpack the definition and intrinsic nature of RKF. We then juxtapose the efficiency of RKF against that of hemodialysis in preserving homeostatic equilibrium and facilitating physiological functions. Given the complex interplay of RKF and overall patient health, we shed light on the extent of its influence on patient outcomes, particularly in those living with advanced kidney dysfunction and on dialysis. This manuscript subsequently presents methodologies and measures to assess RKF, concluding with the potential benefits of targeted interventions aimed at preserving RKF.

Identifiants

pubmed: 39057938
pii: toxins16070298
doi: 10.3390/toxins16070298
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Déclaration de conflit d'intérêts

The authors declare no conflicts of interest. The views, statements, and opinions presented are solely the responsibility of the author(s) and do not necessarily represent the views of PCORI or NIH.

Auteurs

Yoshitsugu Obi (Y)

Division of Nephrology, Department of Medicine, The University of Mississippi Medical Center, Jackson, MS 39216, USA.

Jochen G Raimann (JG)

Renal Research Institute, New York, NY 10065, USA.
Katz School of Science and Health, Yeshiva University, New York, NY 10033, USA.

Kamyar Kalantar-Zadeh (K)

Tibor Rubin Veterans Affairs Long Beach Healthcare System, Long Beach, CA 90822, USA.
The Lundquist Institute at Harbor, UCLA Medical Center, Torrance, CA 90502, USA.
Division of Nephrology, Hypertension, and Kidney Transplantation, University of California Irvine, Orange, CA 92868, USA.

Mariana Murea (M)

Department of Internal Medicine, Section on Nephrology, Wake Forest University School of Medicine, Winston-Salem, NC 27101, USA.

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Classifications MeSH