Multiple embryonic sources converge to form the pectoral girdle skeleton in zebrafish.


Journal

Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555

Informations de publication

Date de publication:
26 Jul 2024
Historique:
received: 27 07 2023
accepted: 19 07 2024
medline: 27 7 2024
pubmed: 27 7 2024
entrez: 26 7 2024
Statut: epublish

Résumé

The morphological transformation of the pectoral/shoulder girdle is fundamental to the water-to-land transition in vertebrate evolution. Although previous studies have resolved the embryonic origins of tetrapod shoulder girdles, those of fish pectoral girdles remain uncharacterized, creating a gap in the understanding of girdle transformation mechanisms from fish to tetrapods. Here, we identify the embryonic origins of the zebrafish pectoral girdle, including the cleithrum as an ancestral girdle element lost in extant tetrapods. Our combinatorial approach of photoconversion and genetic lineage tracing demonstrates that cleithrum development combines four adjoining embryonic populations. A comparison of these pectoral girdle progenitors with extinct and extant vertebrates highlights that cleithrum loss, indispensable for neck evolution, is associated with the disappearance of its unique developmental environment at the head/trunk interface. Overall, our study establishes an embryological framework for pectoral/shoulder girdle formation and provides evolutionary trajectories from their origin in water to diversification on land.

Identifiants

pubmed: 39060278
doi: 10.1038/s41467-024-50734-x
pii: 10.1038/s41467-024-50734-x
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

6313

Informations de copyright

© 2024. The Author(s).

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Auteurs

Shunya Kuroda (S)

Department of Genetics, Rutgers the State University of New Jersey, Piscataway, NJ, 08854, USA. kurodashunya@gmail.com.
Institute for Frontier Science Initiative, Kanazawa University, Kakuma-machi, Kanazawa, 920-1164, Japan. kurodashunya@gmail.com.

Robert L Lalonde (RL)

Department of Pediatrics, Section of Developmental Biology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO, USA.

Thomas A Mansour (TA)

Department of Genetics, Rutgers the State University of New Jersey, Piscataway, NJ, 08854, USA.

Christian Mosimann (C)

Department of Pediatrics, Section of Developmental Biology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO, USA.

Tetsuya Nakamura (T)

Department of Genetics, Rutgers the State University of New Jersey, Piscataway, NJ, 08854, USA. nakamura@dls.rutgers.edu.

Classifications MeSH