Screening Tests for the Interaction of

Rubus sp. additivity antagonisms antibiotics double-disk synergy test extracts synergism

Journal

Antibiotics (Basel, Switzerland)
ISSN: 2079-6382
Titre abrégé: Antibiotics (Basel)
Pays: Switzerland
ID NLM: 101637404

Informations de publication

Date de publication:
15 Jul 2024
Historique:
received: 31 05 2024
revised: 04 07 2024
accepted: 13 07 2024
medline: 27 7 2024
pubmed: 27 7 2024
entrez: 27 7 2024
Statut: epublish

Résumé

WHO (World Health Organization) reports from recent years warn about the growing number of antibiotic-resistant bacterial strains. Therefore, there is an urgent need to constantly search for new substances effective in the fight against microorganisms. Plants are a rich source of chemical compounds with antibacterial properties. These compounds, classified as secondary metabolites, may act independently or support the action of currently used antibiotics. Due to the large number of metabolites isolated from the plant kingdom and new plant species being studied, there is a need to develop new strategies/techniques or modifications of currently applied methods that can be used to select plant extracts or chemical compounds isolated from them that enter into positive, synergistic interactions with currently used antibiotics. One such method is the dual-disk synergy test (DDST). It involves the diffusion of active compounds in the agar environment and influencing the growth of microorganisms grown on it. The method was used to assess the interaction of extracts from the fruit and shoots of some cultivated varieties of

Identifiants

pubmed: 39061335
pii: antibiotics13070653
doi: 10.3390/antibiotics13070653
pii:
doi:

Types de publication

Journal Article

Langues

eng

Auteurs

Rafał Hałasa (R)

Department of Pharmaceutical Microbiology, Medical University of Gdansk, Al. Gen. J. Hallera 107, 80-416 Gdansk, Poland.

Urszula Mizerska (U)

Department of Polymeric Nanomaterials, Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, ul. Sienkiewicza 112, 90-363 Lodz, Poland.

Marta Kula (M)

Moderna Poland sp.zoo, Rondo Ignacego Daszyńskiego 1, 00-843 Warszawa, Poland.

Mirosława Krauze-Baranowska (M)

Department of Pharmacognosy, Medical University of Gdansk, Al. Gen. J. Hallera 107, 80-416 Gdansk, Poland.

Classifications MeSH