Serum and Urinary Uromodulin in Dogs with Early Chronic Kidney Disease vs. Healthy Canine Population.
Tamm–Horsfall protein
biomarker
dog
renal disease
tubular marker
urine
Journal
Animals : an open access journal from MDPI
ISSN: 2076-2615
Titre abrégé: Animals (Basel)
Pays: Switzerland
ID NLM: 101635614
Informations de publication
Date de publication:
18 Jul 2024
18 Jul 2024
Historique:
received:
30
04
2024
revised:
28
06
2024
accepted:
16
07
2024
medline:
27
7
2024
pubmed:
27
7
2024
entrez:
27
7
2024
Statut:
epublish
Résumé
Serum and urinary uromodulin are evaluated as potential biomarkers of kidney disease. The aim of our research was to select a more appropriate form of uromodulin for the diagnosis of early stages of chronic kidney disease (CKD). We also focused on the influence of age and gender in one breed on uromodulin and on the possible interbreed differences. Serum uromodulin had the lowest values in dogs younger than 2 years but no effect of gender, breed, or CKD was observed. Urinary uromodulin indexed to urinary creatinine was significantly reduced in dogs in stage 2 of CKD (
Identifiants
pubmed: 39061561
pii: ani14142099
doi: 10.3390/ani14142099
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Scientific Grant Agency of the Ministry of Education of the Slovak Republic
ID : VEGA 1/0788/19
Organisme : Scientific Grant Agency of the Ministry of Education of the Slovak Republic
ID : VEGA 1/0714/20
Organisme : Scientific Grant Agency of the Ministry of Education of the Slovak Republic
ID : VEGA 1/0668/24