The Analysis of ECE1 and PPARG Variants in the Development of Osteopenia and Osteoporosis in Postmenopausal Women.

ECE1 PPARG allelic variants osteoporosis polymerase chain reaction

Journal

Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304

Informations de publication

Date de publication:
27 Jun 2024
Historique:
received: 16 05 2024
revised: 03 06 2024
accepted: 21 06 2024
medline: 27 7 2024
pubmed: 27 7 2024
entrez: 27 7 2024
Statut: epublish

Résumé

Osteoporosis is a multifactorial systemic skeletal disease that is characterized by a low bone mineral density (BMD) and the microarchitectural deterioration of bone tissue, leading to bone fragility. The search for new genes that may play an important role in the regulation of bone mass and the development of osteoporosis is ongoing. Recently, it was found that altering the activity of the endothelin-1-converting enzyme encoded by the

Identifiants

DOI: 10.3390/biomedicines12071440 PMID: 39062013
pubmed: 39062013
pii: biomedicines12071440
doi: 10.3390/biomedicines12071440
pii:
doi:

Types de publication

Journal Article

Langues

eng

Auteurs

Izabela Uzar (I)

Department of General Pharmacology and Pharmacoeconomics, Pomeranian Medical University in Szczecin, Żołnierska 48, 71-230 Szczecin, Poland.
Department of Pharmacology and Toxicology, Institute of Health Sciences, Collegium Medicum, University of Zielona Góra, Zyty 28, 65-048 Zielona Góra, Poland.

Anna Bogacz (A)

Department of Personalized Medicine and Cell Therapy, Regional Blood Center, Marcelinska 44, 60-354 Poznan, Poland.
ORCID: 0000-0001-5455-8315

Małgorzata Łuszczyńska (M)

Department of Stem Cells and Regenerative Medicine, Institute of Natural Fibres and Medicinal Plants, Kolejowa 2, 62-064 Plewiska, Poland.

Marlena Wolek (M)

Department of Stem Cells and Regenerative Medicine, Institute of Natural Fibres and Medicinal Plants, Kolejowa 2, 62-064 Plewiska, Poland.

Katarzyna Kotrych (K)

Department of General and Dental Radiology, Pomeranian Medical University in Szczecin, Powstańców Wielkopolskich 72, 70-111 Szczecin, Poland.
ORCID: 0000-0002-1391-4499

Andrzej Modrzejewski (A)

Clinical Department of General Surgery, Pomeranian Medical University in Szczecin, Piotra Skargi 9-11, 70-965 Szczecin, Poland.

Bogusław Czerny (B)

Department of General Pharmacology and Pharmacoeconomics, Pomeranian Medical University in Szczecin, Żołnierska 48, 71-230 Szczecin, Poland.
Department of Stem Cells and Regenerative Medicine, Institute of Natural Fibres and Medicinal Plants, Kolejowa 2, 62-064 Plewiska, Poland.

Paweł Ziętek (P)

Department of Orthopaedics, Traumatology and Orthopaedic Oncology, Pomeranian Medical University in Szczecin, Unii Lubelskiej 1, 71-252 Szczecin, Poland.

Adam Kamiński (A)

Department of Orthopedics and Traumatology, Independent Public Clinical Hospital No. 1, Pomeranian Medical University in Szczecin, Unii Lubelskiej 1, 71-252 Szczecin, Poland.

Classifications MeSH