Dopamine Receptors and TAAR1 Functional Interaction Patterns in the Duodenum Are Impaired in Gastrointestinal Disorders.

DRD2 DRD4 DRD5 TAAR1 diabetic gastroparesis dopamine duodenum functional dyspepsia trace amines

Journal

Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304

Informations de publication

Date de publication:
17 Jul 2024
Historique:
received: 24 05 2024
revised: 20 06 2024
accepted: 15 07 2024
medline: 27 7 2024
pubmed: 27 7 2024
entrez: 27 7 2024
Statut: epublish

Résumé

Currently, there is a growing amount of evidence for the involvement of dopamine receptors and the functionally related trace amine-associated receptor, TAAR1, in upper intestinal function. In the present study, we analyzed their expression in the duodenum using publicly accessible transcriptomic data. We revealed the expression of

Identifiants

DOI: 10.3390/biomedicines12071590 PMID: 39062162
pubmed: 39062162
pii: biomedicines12071590
doi: 10.3390/biomedicines12071590
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Russian Science Foundation
ID : 19-75-30008-P

Auteurs

Anastasia N Vaganova (AN)

Institute of Translational Biomedicine, St. Petersburg State University, Universitetskaya nab. 7/9, 199034 St. Petersburg, Russia.
St. Petersburg State University Hospital, St. Petersburg State University, Universitetskaya nab. 7/9, 199034 St. Petersburg, Russia.
ORCID: 0000-0002-0101-1065

Alisa A Markina (AA)

Institute of Translational Biomedicine, St. Petersburg State University, Universitetskaya nab. 7/9, 199034 St. Petersburg, Russia.

Aleksandr M Belousov (AM)

St. Petersburg State University Hospital, St. Petersburg State University, Universitetskaya nab. 7/9, 199034 St. Petersburg, Russia.

Karina V Lenskaia (KV)

Department of Medicine, St. Petersburg State University, Universitetskaya nab. 7/9, 199034 St. Petersburg, Russia.

Raul R Gainetdinov (RR)

Institute of Translational Biomedicine, St. Petersburg State University, Universitetskaya nab. 7/9, 199034 St. Petersburg, Russia.
St. Petersburg State University Hospital, St. Petersburg State University, Universitetskaya nab. 7/9, 199034 St. Petersburg, Russia.

Classifications MeSH