Structural Basis for the Interaction between the Ezrin FERM-Domain and Human Aquaporins.

Aquaporin 2 Aquaporin 5 FERM ezrin in silico modelling membrane protein trafficking microscale thermophoresis protein–protein interactions

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
12 Jul 2024
Historique:
received: 20 06 2024
revised: 08 07 2024
accepted: 09 07 2024
medline: 27 7 2024
pubmed: 27 7 2024
entrez: 27 7 2024
Statut: epublish

Résumé

The Ezrin/Radixin/Moesin (ERM) family of proteins act as cross-linkers between the plasma membrane and the actin cytoskeleton. This mechanism plays an essential role in processes related to membrane remodeling and organization, such as cell polarization, morphogenesis and adhesion, as well as in membrane protein trafficking and signaling pathways. For several human aquaporin (AQP) isoforms, an interaction between the ezrin band

Identifiants

pubmed: 39062914
pii: ijms25147672
doi: 10.3390/ijms25147672
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Crafoord Foundation
ID : 2018-0916
Organisme : Swedish Research Council
ID : 2019-06106
Organisme : Swedish Research Council for Environment Agricultural Sciences and Spatial Planning
ID : 2017-01463

Auteurs

Helin Strandberg (H)

Department of Biochemistry and Structural Biology, Lund University, 221 00 Lund, Sweden.

Carl Johan Hagströmer (CJ)

Department of Biochemistry and Structural Biology, Lund University, 221 00 Lund, Sweden.

Balder Werin (B)

Department of Biochemistry and Structural Biology, Lund University, 221 00 Lund, Sweden.

Markus Wendler (M)

Department of Biochemistry and Structural Biology, Lund University, 221 00 Lund, Sweden.

Urban Johanson (U)

Department of Biochemistry and Structural Biology, Lund University, 221 00 Lund, Sweden.

Susanna Törnroth-Horsefield (S)

Department of Biochemistry and Structural Biology, Lund University, 221 00 Lund, Sweden.

Classifications MeSH