Selective Antineoplastic Potential of Fractionated Caribbean Native

Ganoderma martinicense Ganoderma multiplicatum MCF-10A SUM149PT cytotoxicity fractions natural product triple-negative breast cancer

Journal

Pharmaceuticals (Basel, Switzerland)
ISSN: 1424-8247
Titre abrégé: Pharmaceuticals (Basel)
Pays: Switzerland
ID NLM: 101238453

Informations de publication

Date de publication:
01 Jul 2024
Historique:
received: 07 06 2024
revised: 24 06 2024
accepted: 25 06 2024
medline: 27 7 2024
pubmed: 27 7 2024
entrez: 27 7 2024
Statut: epublish

Résumé

Triple-negative breast cancer (TNBC) is an aggressive subtype characterized by the absence of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor type 2 expression. It is known for its high malignancy, invasiveness, and propensity for metastasis, resulting in a poor prognosis due to the absence of beneficial therapeutic targets. Natural products derived from mushrooms have gained significant attention in neoplastic therapy due to their potential medicinal properties. The therapeutic potential of

Identifiants

pubmed: 39065715
pii: ph17070864
doi: 10.3390/ph17070864
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : NIH HHS
ID : R16GM145488
Pays : United States
Organisme : NIH HHS
ID : SC3GM111171
Pays : United States
Organisme : NIH HHS
ID : U54GM133807
Pays : United States
Organisme : NIH HHS
ID : S21MD001830
Pays : United States
Organisme : U.S. Department of Agriculture/National Institute of Food and Agriculture/Small Business Innovation Research
ID : 2022-33530-37064
Organisme : Puerto Rico Science, Technology & Research Trust Therapeutic Accelerator Program
ID : 2022-00121
Organisme : Susan G. Komen ASPIRE
ID : ASP231046822

Déclaration de conflit d'intérêts

The authors declare no conflicts of interest.

Auteurs

Luz V Arroyo-Cruz (LV)

Department of Biochemistry, School of Medicine, Universidad Central del Caribe, Bayamón 00960-6032, Puerto Rico.

Sebastián Sagardía-González (S)

Huerto Rico, Carolina 00987, Puerto Rico.

Kurt Miller (K)

Huerto Rico, Carolina 00987, Puerto Rico.

Taotao Ling (T)

Department of Chemistry, Louisiana State University, 133 Choppin Hall, Baton Rouge, LA 70803, USA.

Fatima Rivas (F)

Department of Chemistry, Louisiana State University, 133 Choppin Hall, Baton Rouge, LA 70803, USA.

Michelle M Martínez-Montemayor (MM)

Department of Biochemistry, School of Medicine, Universidad Central del Caribe, Bayamón 00960-6032, Puerto Rico.

Classifications MeSH