Psychometric validation of the Chinese versions of EQ-5D-Y-3L and the experimental EQ-TIPS in children and adolescents with COVID-19.

COVID-19 EQ-5D-Y-3L EQ-TIPS Health-related quality of life Validation

Journal

The European journal of health economics : HEPAC : health economics in prevention and care
ISSN: 1618-7601
Titre abrégé: Eur J Health Econ
Pays: Germany
ID NLM: 101134867

Informations de publication

Date de publication:
27 Jul 2024
Historique:
received: 19 03 2024
accepted: 01 07 2024
medline: 28 7 2024
pubmed: 28 7 2024
entrez: 27 7 2024
Statut: aheadofprint

Résumé

Respiratory infectious diseases like COVID-19 profoundly impacts the health of children and adolescents, but validated instruments to measure their impacts on health-related quality of life (HRQoL) are lacking. The EQ-5D-Y-3L, widely used for youth HRQoL, now features a Chinese value set. The experimental EQ-TIPS addresses HRQoL assessment for toddlers and infants. This study tested the psychometric properties of both instruments in paediatric COVID-19 patients, and compared the performance of self-complete and proxy EQ-5D-Y-3L. This longitudinal study recruited 861 COVID-19 patients aged 0-18 years and their parental caregivers, with 311 dyads completing the follow-up. Digital administration included the EQ-TIPS, the EQ-5D-Y-3L, and Overall Health Assessment (OHA). Controls comprised 231 healthy children. Analysis encompassed known-group validity, child-parent agreement, and responsiveness to change in disease severity and OHA. COVID-19 children exhibited lower HRQoL than non-infected peers. The EQ-TIPS and the EQ-5D-Y-3L distinguished groups by disease presence, severity and symptoms, showing moderate to good known-group validity (ESs: 0.45-1.39 for EQ-TIPS, 0.44-1.91 for self-complete EQ-5D-Y-3L, and 0.32-1.67 for proxy EQ-5D-Y-3L). Child-parent agreement was moderate to good for EQ-5D-Y-3L (ICC: 0.653-0.823; Gwet's AC1: 0.470-0.738), and responsiveness was good for both EQ-TIPS Level Sum Score (LSS) (ESs: 1.21-1.39) and EQ-5D-Y-3L index scores (ESs: 1.00-1.16). This study demonstrates the reliability, validity, and responsiveness of the experimental EQ-TIPS and the EQ-5D-Y-3L in paediatric COVID-19 patients. It is the first evidence of the EQ-TIPS' responsiveness, supporting its use in assessing the impact of COVID-19 on paediatric HRQoL.

Identifiants

pubmed: 39066840
doi: 10.1007/s10198-024-01710-1
pii: 10.1007/s10198-024-01710-1
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : EuroQol Research Foundation
ID : EQ Project 1654-TVG

Informations de copyright

© 2024. The Author(s).

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Auteurs

Wenjing Zhou (W)

Department of Paediatrics, Renji Hospital, School of Medicine, Shanghai Jiaotong University, No. 2000, Jiangyue Road, Shanghai, China. zhoujing2188@163.com.
Department of Psychiatry, Section Medical Psychology and Psychotherapy, Erasmus Medical Center, Rotterdam, The Netherlands. zhoujing2188@163.com.

Yaqin Li (Y)

Department of Paediatrics, Renji Hospital, School of Medicine, Shanghai Jiaotong University, No. 2000, Jiangyue Road, Shanghai, China.

Jan Busschbach (J)

Department of Psychiatry, Section Medical Psychology and Psychotherapy, Erasmus Medical Center, Rotterdam, The Netherlands.

Michael Herdman (M)

Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.

Zhihao Yang (Z)

Health Services Management Department, Guizhou Medical University, Guiyang, China.

Yanming Lu (Y)

Department of Paediatrics, Renji Hospital, School of Medicine, Shanghai Jiaotong University, No. 2000, Jiangyue Road, Shanghai, China. luyanming@renji.com.

Classifications MeSH