Male Reproductive Endocrine Disorders.
Erectile dysfunction
Exogenous testosterone supplementation
Gynecomastia
Hypogonadism
Hypothalamic–pituitary–gonadal axis
Low testosterone
Journal
Primary care
ISSN: 1558-299X
Titre abrégé: Prim Care
Pays: United States
ID NLM: 0430463
Informations de publication
Date de publication:
Sep 2024
Sep 2024
Historique:
medline:
28
7
2024
pubmed:
28
7
2024
entrez:
27
7
2024
Statut:
ppublish
Résumé
The endocrine system intricately regulates male sexual development and health which influences masculinization, sexual libido, muscle mass, bone density, and overall vitality. Disorders in the hypothalamic-pituitary-gonadal axis can lead to hypogonadism, gynecomastia, sexual dysfunction, and infertility. Testosterone replacement therapy can be considered for symptomatic hypogonadism but poses risks for azoospermia and polycythemia, along with uncertain impact on cardiovascular disease. Gynecomastia results from a high estrogen-to-androgen ratio, mostly from either excess estrogen or decreased androgens. Sexual dysfunction is more commonly secondary to psychological or metabolic disorders; consider workups to rule out endocrine etiologies including hypogonadism if indicated.
Identifiants
pubmed: 39067971
pii: S0095-4543(24)00031-9
doi: 10.1016/j.pop.2024.04.003
pii:
doi:
Substances chimiques
Testosterone
3XMK78S47O
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
455-466Informations de copyright
Copyright © 2024 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Disclosure The authors have nothing to disclose.