Spectral characterization of intraoperative renal perfusion using hyperspectral imaging and artificial intelligence.

Animals Swine Kidney / blood supply Hyperspectral Imaging / methods Humans Artificial Intelligence Nephrectomy / methods Perfusion / methods
Hyperspectral imaging Machine learning Porcine model Renal malperfusion Renal perfusion Surgery Surgical data science Translational research

Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
27 Jul 2024
Historique:
received: 27 03 2024
accepted: 22 07 2024
medline: 28 7 2024
pubmed: 28 7 2024
entrez: 27 7 2024
Statut: epublish

Résumé

Accurate intraoperative assessment of organ perfusion is a pivotal determinant in preserving organ function e.g. during kidney surgery including partial nephrectomy or kidney transplantation. Hyperspectral imaging (HSI) has great potential to objectively describe and quantify this perfusion as opposed to conventional surrogate techniques such as ultrasound flowmeter, indocyanine green or the subjective eye of the surgeon. An established live porcine model under general anesthesia received median laparotomy and renal mobilization. Different scenarios that were measured using HSI were (1) complete, (2) gradual and (3) partial malperfusion. The differences in spectral reflectance as well as HSI oxygenation (StO

Identifiants

DOI: 10.1038/s41598-024-68280-3 PMID: 39068299
pubmed: 39068299
doi: 10.1038/s41598-024-68280-3
pii: 10.1038/s41598-024-68280-3
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

17262

Informations de copyright

© 2024. The Author(s).

Références

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Auteurs

A Studier-Fischer (A)

Department of General, Visceral, and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany. alexander@studier-fischer.com.
Department of Urology and Urosurgery, Medical Faculty of the University of Heidelberg, University Medical Center Mannheim, Mannheim, Germany. alexander@studier-fischer.com.
Division of Intelligent Systems and Robotics in Urology (ISRU), German Cancer Research Center (DKFZ) Heidelberg, Heidelberg, Germany. alexander@studier-fischer.com.
DKFZ Hector Cancer Institute at the University Medical Center Mannheim, Mannheim, Germany. alexander@studier-fischer.com.

M Bressan (M)

Department of General, Visceral, and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany.

A Bin Qasim (AB)

Division of Intelligent Medical Systems, German Cancer Research Center (DKFZ) Heidelberg, Heidelberg, Germany.
HIDSS4Health - Helmholtz Information and Data Science School for Health, Karlsruhe, Heidelberg, Germany.
National Center for Tumor Diseases (NCT) Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg, Germany.

B Özdemir (B)

Department of General, Visceral, and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany.
Division of Intelligent Systems and Robotics in Urology (ISRU), German Cancer Research Center (DKFZ) Heidelberg, Heidelberg, Germany.
DKFZ Hector Cancer Institute at the University Medical Center Mannheim, Mannheim, Germany.

J Sellner (J)

Division of Intelligent Medical Systems, German Cancer Research Center (DKFZ) Heidelberg, Heidelberg, Germany.
HIDSS4Health - Helmholtz Information and Data Science School for Health, Karlsruhe, Heidelberg, Germany.
National Center for Tumor Diseases (NCT) Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg, Germany.
Faculty of Mathematics and Computer Science, Heidelberg University, Heidelberg, Germany.

S Seidlitz (S)

Division of Intelligent Medical Systems, German Cancer Research Center (DKFZ) Heidelberg, Heidelberg, Germany.
HIDSS4Health - Helmholtz Information and Data Science School for Health, Karlsruhe, Heidelberg, Germany.
National Center for Tumor Diseases (NCT) Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg, Germany.
Faculty of Mathematics and Computer Science, Heidelberg University, Heidelberg, Germany.

C M Haney (CM)

Department of Urology and Urosurgery, Medical Faculty of the University of Heidelberg, University Medical Center Mannheim, Mannheim, Germany.
Division of Intelligent Systems and Robotics in Urology (ISRU), German Cancer Research Center (DKFZ) Heidelberg, Heidelberg, Germany.
DKFZ Hector Cancer Institute at the University Medical Center Mannheim, Mannheim, Germany.

L Egen (L)

Department of Urology and Urosurgery, Medical Faculty of the University of Heidelberg, University Medical Center Mannheim, Mannheim, Germany.
Division of Intelligent Systems and Robotics in Urology (ISRU), German Cancer Research Center (DKFZ) Heidelberg, Heidelberg, Germany.
DKFZ Hector Cancer Institute at the University Medical Center Mannheim, Mannheim, Germany.

M Michel (M)

Department of Urology and Urosurgery, Medical Faculty of the University of Heidelberg, University Medical Center Mannheim, Mannheim, Germany.
Division of Intelligent Systems and Robotics in Urology (ISRU), German Cancer Research Center (DKFZ) Heidelberg, Heidelberg, Germany.
DKFZ Hector Cancer Institute at the University Medical Center Mannheim, Mannheim, Germany.

M Dietrich (M)

Department of Anesthesiology, Heidelberg University Hospital, Heidelberg, Germany.

G A Salg (GA)

Department of General, Visceral, and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany.

F Billmann (F)

Department of General, Visceral, and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany.

H Nienhüser (H)

Department of General, Visceral, and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany.

T Hackert (T)

Department of General, Visceral, and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

B P Müller (BP)

Department of Digestive Surgery, University Digestive Healthcare Center, Basel, Switzerland.

L Maier-Hein (L)

Division of Intelligent Medical Systems, German Cancer Research Center (DKFZ) Heidelberg, Heidelberg, Germany.
HIDSS4Health - Helmholtz Information and Data Science School for Health, Karlsruhe, Heidelberg, Germany.
National Center for Tumor Diseases (NCT) Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg, Germany.
Faculty of Mathematics and Computer Science, Heidelberg University, Heidelberg, Germany.

F Nickel (F)

Department of General, Visceral, and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany.
HIDSS4Health - Helmholtz Information and Data Science School for Health, Karlsruhe, Heidelberg, Germany.
Department of General, Visceral, and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

K F Kowalewski (KF)

Department of Urology and Urosurgery, Medical Faculty of the University of Heidelberg, University Medical Center Mannheim, Mannheim, Germany.
Division of Intelligent Systems and Robotics in Urology (ISRU), German Cancer Research Center (DKFZ) Heidelberg, Heidelberg, Germany.
DKFZ Hector Cancer Institute at the University Medical Center Mannheim, Mannheim, Germany.

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Classifications MeSH

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