Novel nano composites from Citrus limon and Citrullus colocynthis agricultural wastes for biomedical applications.
Citrus
/ chemistry
Nanocomposites
/ chemistry
Humans
Citrullus colocynthis
/ chemistry
Candida albicans
/ drug effects
Anti-Infective Agents
/ pharmacology
Staphylococcus aureus
/ drug effects
Polyvinyl Alcohol
/ chemistry
Escherichia coli
/ drug effects
Agriculture
/ methods
Cell Line
Starch
/ chemistry
Microbial Sensitivity Tests
Spectroscopy, Fourier Transform Infrared
Citrullus colocynthis
Citrus limon
Biocompatibility
Biofillers
Dielectric spectroscopy
Polymer nanocomposite
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
28 Jul 2024
28 Jul 2024
Historique:
received:
23
03
2024
accepted:
11
07
2024
medline:
29
7
2024
pubmed:
29
7
2024
entrez:
28
7
2024
Statut:
epublish
Résumé
In recent years, academic and industrial research has focused on using agro-waste for energy and new material production to promote sustainable development and lessen environmental issues. In this study, new nanocomposites based on polyvinyl alcohol (PVA)-Starch using two affordable agricultural wastes, Citrus limon peels (LP) and Citrullus colocynthis (Cc) shells and seeds powders with different concentrations (2, 5, 10, and 15 wt%) as bio-fillers were prepared. The nanocomposites were characterized by Dielectric Spectroscopy, Fourier-Transform Infrared (FTIR), Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), and water swelling ratio. The antimicrobial properties of the nanocomposites against Escherichia coli, Staphylococcus aureus, and Candida albicans were examined to investigate the possibility of using such composites in biomedical applications. Additionally, the biocompatibility of the composites on human normal fibroblast cell lines (HFB4) was tested using MTT (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide) assay. The results demonstrate that the filler type and concentration strongly affect the film's properties. The permittivity ε', dielectric loss ε″ and conductivity σ
Identifiants
pubmed: 39069554
doi: 10.1038/s41598-024-67423-w
pii: 10.1038/s41598-024-67423-w
doi:
Substances chimiques
Anti-Infective Agents
0
Polyvinyl Alcohol
9002-89-5
Starch
9005-25-8
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
17343Informations de copyright
© 2024. The Author(s).
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