Isocitrate Dehydrogenase (IDH)-Mutant High-Grade Glioma in the Cerebellum: A Case Report.

cerebellar high-grade glioma intra axial lesion isocitrate dehydrogenase supra tentorial

Journal

Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737

Informations de publication

Date de publication:
Jun 2024
Historique:
accepted: 27 06 2024
medline: 29 7 2024
pubmed: 29 7 2024
entrez: 29 7 2024
Statut: epublish

Résumé

High-grade glial cancers typically arise in the cerebral hemisphere and rarely in the cerebellum. Our objective was to highlight the diagnostic features of isocitrate dehydrogenase (IDH)-mutant high-grade gliomas in the cerebellum. We present a case of an elderly patient admitted with giddiness who was diagnosed with IDH-mutant high-grade glioma in the cerebellum, presenting as multiple lesions. We evaluated an open biopsy specimen to arrive at a diagnosis and used molecular studies to confirm the diagnosis and further categorize the specimens. Histopathology and immunohistochemistry confirmed the diagnosis of IDH-mutant high-grade glioma in the cerebellum.

Identifiants

pubmed: 39070490
doi: 10.7759/cureus.63335
pmc: PMC11283592
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Pagination

e63335

Informations de copyright

Copyright © 2024, Dinesh et al.

Déclaration de conflit d'intérêts

Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

Auteurs

Divya Dinesh (D)

Pathology, Sree Balaji Medical College and Hospital, Chennai, IND.

Thanka Johnson (T)

Pathology, Sree Balaji Medical College and Hospital, Chennai, IND.

Divyalakshmi P K (D)

Pathology, Sree Balaji Medical College and Hospital, Chennai, IND.

Santhanam Rengarajan (S)

Neurosurgery, Sree Balaji Medical College and Hospital, Chennai, IND.

Venkatraman Indiran (V)

Radiodiagnosis, Sree Balaji Medical College and Hospital, Chennai, IND.

Classifications MeSH