Mechanically Stable and Biocompatible Polymer Brush Coated Dental Materials with Lubricious and Antifouling Properties.

ATRP antifouling friction polymer brush surface‐initiated polymerization

Journal

Macromolecular bioscience
ISSN: 1616-5195
Titre abrégé: Macromol Biosci
Pays: Germany
ID NLM: 101135941

Informations de publication

Date de publication:
29 Jul 2024
Historique:
revised: 24 06 2024
received: 19 04 2024
medline: 29 7 2024
pubmed: 29 7 2024
entrez: 29 7 2024
Statut: aheadofprint

Résumé

Surface modification plays a crucial role in enhancing the functionality of implanted interventional medical devices, offering added advantages to patients, particularly in terms of lubrication and prevention of undesired adsorption of biomolecules and microorganisms, such as proteins and bacteria, on the material surfaces. Utilizing polymer brushes for surface modification is currently a promising approach to maintaining the inherent properties of materials while introducing new functionalities to surfaces. Here, surface-initiated atom transfer radical polymerization (SI-ATRP) technology to effectively graft anionic, cationic, and neutral polymer brushes from a mixed silane initiating layer is employed. The presence of a polymer brush layer significantly enhances the lubrication performance of the substrates and ensures a consistently low coefficient of friction over thousands of friction cycles in aqueous environments. The antimicrobial efficacy of polymer brushes is evaluated against gram-positive Staphylococcus aureus (S. aureus) and gram-negative Escherichia coli (E. coli). It is observed that polym er brushes grafted to diverse substrate surfaces displays notable antibacterial properties, effectively inhibiting bacterial attachment. Furthermore, the polymer brush layer shows favorable biocompatibility and anti-inflammatory characteristics, which shows potential applications in dental materials, and other fields such as catheters and food packaging.

Identifiants

pubmed: 39073313
doi: 10.1002/mabi.202400194
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2400194

Subventions

Organisme : Shandong Provincial Natural Science Foundation
ID : ZR2023JQ023
Organisme : Fundamental Research Funds for The Central Universities
ID : 31920220160

Informations de copyright

© 2024 Wiley‐VCH GmbH.

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Auteurs

Rong Mu (R)

School of Chemical Engineering, Northwest Minzu University, Lanzhou, 730000, China.

Ling Yang (L)

School of Stomatology, Lanzhou University, Lanzhou, 730000, China.

Xinyue Wang (X)

School of Stomatology, Lanzhou University, Lanzhou, 730000, China.

Binrui Yang (B)

State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, China.

Jia Li (J)

School of Chemical Engineering, Northwest Minzu University, Lanzhou, 730000, China.

Aijun Wang (A)

School of Chemical Engineering, Northwest Minzu University, Lanzhou, 730000, China.

Guorui Zhang (G)

State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, China.

Chufeng Sun (C)

School of Chemical Engineering, Northwest Minzu University, Lanzhou, 730000, China.

Yang Wu (Y)

State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, China.
Shandong Laboratory of Advanced Materials and Green Manufacturing at Yantai, Yantai, 264000, China.

Bo Yu (B)

State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, China.

Bin Li (B)

State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, China.
Shandong Laboratory of Advanced Materials and Green Manufacturing at Yantai, Yantai, 264000, China.

Classifications MeSH