The Predictive Role of the Triglyceride/Glucose Index in Patients with Hypercholesterolemia and Acute Ischemic Stroke.
hypercholesterolemia
insulin resistance
ischemic stroke
outcome
prognosis
severity
triglyceride/glucose index
Journal
Reviews in cardiovascular medicine
ISSN: 1530-6550
Titre abrégé: Rev Cardiovasc Med
Pays: Singapore
ID NLM: 100960007
Informations de publication
Date de publication:
Dec 2022
Dec 2022
Historique:
received:
21
07
2022
revised:
08
11
2022
accepted:
10
11
2022
medline:
9
12
2022
pubmed:
9
12
2022
entrez:
30
7
2024
Statut:
epublish
Résumé
The triglyceride/glucose index (TyG) reflects insulin resistance and predicts the risk of acute ischemic stroke (aIS). However, it is uncertain if this index predicts the severity and outcome of aIS because studies that addressed this question are few and all were performed in Asian subjects. Moreover, there are no studies that focused on patients with hypercholesterolemia. We studied 997 Caucasian patients who were hospitalized for aIS and had hypercholesterolemia. aIS severity was assessed at admission with the National Institutes of Health Stroke Scale (NIHSS) and severe aIS was defined as NIHSS The TyG index did not correlate with the NIHSS at admission (r = 0.032, The TyG index does not appear to be associated with the severity or the outcome of aIS. Nevertheless, since there are few relevant data in Caucasians and the TyG index is an inexpensive and widely available biomarker, more studies in this ethnic group are required to determine the predictive role of this index in patients with aIS.
Sections du résumé
Background
UNASSIGNED
The triglyceride/glucose index (TyG) reflects insulin resistance and predicts the risk of acute ischemic stroke (aIS). However, it is uncertain if this index predicts the severity and outcome of aIS because studies that addressed this question are few and all were performed in Asian subjects. Moreover, there are no studies that focused on patients with hypercholesterolemia.
Methods
UNASSIGNED
We studied 997 Caucasian patients who were hospitalized for aIS and had hypercholesterolemia. aIS severity was assessed at admission with the National Institutes of Health Stroke Scale (NIHSS) and severe aIS was defined as NIHSS
Results
UNASSIGNED
The TyG index did not correlate with the NIHSS at admission (r = 0.032,
Conclusions
UNASSIGNED
The TyG index does not appear to be associated with the severity or the outcome of aIS. Nevertheless, since there are few relevant data in Caucasians and the TyG index is an inexpensive and widely available biomarker, more studies in this ethnic group are required to determine the predictive role of this index in patients with aIS.
Identifiants
pubmed: 39076671
doi: 10.31083/j.rcm2312399
pii: S1530-6550(22)00763-3
pmc: PMC11270394
doi:
Types de publication
Journal Article
Langues
eng
Pagination
399Informations de copyright
Copyright: © 2022 The Author(s). Published by IMR Press.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest. Konstantinos Tziomalos is serving as Guest Editor of this journal. We declare that Konstantinos Tziomalos had no involvement in the peer review of this article and has no access to information regarding its peer review. Full responsibility for the editorial process for this article was delegated to Brian Tomlinson.