Association between Dental and Cardiovascular Diseases: A Systematic Review.
cardiovascular disease
clinical trials
dental
infection
tooth disease
Journal
Reviews in cardiovascular medicine
ISSN: 1530-6550
Titre abrégé: Rev Cardiovasc Med
Pays: Singapore
ID NLM: 100960007
Informations de publication
Date de publication:
Jun 2023
Jun 2023
Historique:
received:
25
07
2022
revised:
09
09
2022
accepted:
13
09
2022
medline:
6
6
2023
pubmed:
6
6
2023
entrez:
30
7
2024
Statut:
epublish
Résumé
The link between dental, infective and obstructive cardiovascular diseases is debatable. To systematically review the literature to assess the association between dental conditions and development of cardiovascular disease. The systematic review was conducted following the PRISMA guidelines using PubMed (Medline), Web of Science, Scopus, EMBASE and SciELO. Out of 6680 records, 82 articles were eligible for inclusion after reviewing titles and abstracts. No association between dental disease and cardiovascular disease has been observed in 10 studies while a potential link has been suggested by the remaining trials. Tooth loss and periodontitis are the main evaluated oral conditions while coronary artery disease, stroke, atherosclerosis and myocardial infarction represent the major cardiovascular events. The interaction between these two clinical entities is based on direct mechanism mediated by systemic inflammatory response, leakage of cytokines and endothelial cells invasion by oral pathogens and indirect mechanism mediated by common risk factors or confounders. It seems that tooth loss, periodontitis and poor oral hygiene increase the risk of atherosclerotic cardiovascular events, and subsequently oral health care professionals could contribute to public health cardiovascular control efforts.
Sections du résumé
Background
UNASSIGNED
The link between dental, infective and obstructive cardiovascular diseases is debatable.
Aim
UNASSIGNED
To systematically review the literature to assess the association between dental conditions and development of cardiovascular disease.
Methods
UNASSIGNED
The systematic review was conducted following the PRISMA guidelines using PubMed (Medline), Web of Science, Scopus, EMBASE and SciELO.
Results
UNASSIGNED
Out of 6680 records, 82 articles were eligible for inclusion after reviewing titles and abstracts. No association between dental disease and cardiovascular disease has been observed in 10 studies while a potential link has been suggested by the remaining trials. Tooth loss and periodontitis are the main evaluated oral conditions while coronary artery disease, stroke, atherosclerosis and myocardial infarction represent the major cardiovascular events. The interaction between these two clinical entities is based on direct mechanism mediated by systemic inflammatory response, leakage of cytokines and endothelial cells invasion by oral pathogens and indirect mechanism mediated by common risk factors or confounders.
Conclusions
UNASSIGNED
It seems that tooth loss, periodontitis and poor oral hygiene increase the risk of atherosclerotic cardiovascular events, and subsequently oral health care professionals could contribute to public health cardiovascular control efforts.
Identifiants
pubmed: 39077523
doi: 10.31083/j.rcm2406159
pii: S1530-6550(22)00703-7
pmc: PMC11264166
doi:
Types de publication
Journal Article
Systematic Review
Langues
eng
Pagination
159Informations de copyright
Copyright: © 2023 The Author(s). Published by IMR Press.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest. Anthony Matta and Jerome Roncalli are serving as Guest Editors of this journal. We declare that Anthony Matta and Jerome Roncalli had no involvement in the peer review of this article and has no access to information regarding its peer review. Full responsibility for the editorial process for this article was delegated to Gary Tse, Sharen Lee and Tong Liu.