Central and Peripheral Circulation Differ during Off-Pump Coronary Artery Bypass Grafting.

CABG OPCAB cutaneous oxygen partial pressure microcirculation perfusion

Journal

Reviews in cardiovascular medicine
ISSN: 1530-6550
Titre abrégé: Rev Cardiovasc Med
Pays: Singapore
ID NLM: 100960007

Informations de publication

Date de publication:
Jan 2024
Historique:
received: 09 10 2023
revised: 06 12 2023
accepted: 18 12 2023
medline: 30 7 2024
pubmed: 30 7 2024
entrez: 30 7 2024
Statut: epublish

Résumé

Off-pump coronary artery bypass grafting (OPCAB) is an alternative to on-pump coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB). During OPCAB, the temporary use of an intracoronary shunt and inotropic medication or catecholamines should keep the central hemodynamics constant. Nevertheless, the need for conversion to on-pump CABG often occurs unexpectedly, most likely due to circulation instability. Circulation instability can appear first in peripheral body parts; therefore, peripheral microcirculation might serve as a predictor for the upcoming conversion to on-pump CABG. We investigated the impact of coronary artery ligation and shunt insertion during OPCAB on cutaneous microcirculation (cLDP) with Laser Doppler Perfusion Technology and transcutaneous oxygen partial pressure ( In a pig model of OPCAB, peripheral circulation was evaluated after cLDP (N = 17) and Ligation time during cLDP and Although hemodynamic parameters stayed constant, peripheral microcirculation was influenced markedly during OPCAB. Inserting a temporary shut into the LAD leads to a complete normalization of peripheral microcirculation, regarding evaluation by cLDP and

Sections du résumé

Background UNASSIGNED
Off-pump coronary artery bypass grafting (OPCAB) is an alternative to on-pump coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB). During OPCAB, the temporary use of an intracoronary shunt and inotropic medication or catecholamines should keep the central hemodynamics constant. Nevertheless, the need for conversion to on-pump CABG often occurs unexpectedly, most likely due to circulation instability. Circulation instability can appear first in peripheral body parts; therefore, peripheral microcirculation might serve as a predictor for the upcoming conversion to on-pump CABG. We investigated the impact of coronary artery ligation and shunt insertion during OPCAB on cutaneous microcirculation (cLDP) with Laser Doppler Perfusion Technology and transcutaneous oxygen partial pressure (
Methods UNASSIGNED
In a pig model of OPCAB, peripheral circulation was evaluated after cLDP (N = 17) and
Results UNASSIGNED
Ligation time during cLDP and
Conclusions UNASSIGNED
Although hemodynamic parameters stayed constant, peripheral microcirculation was influenced markedly during OPCAB. Inserting a temporary shut into the LAD leads to a complete normalization of peripheral microcirculation, regarding evaluation by cLDP and

Identifiants

DOI: 10.31083/j.rcm2501030 PMID: 39077659 PMC: PMC11262409
pubmed: 39077659
doi: 10.31083/j.rcm2501030
pii: S1530-6550(23)01269-3
pmc: PMC11262409
doi:

Types de publication

Journal Article

Langues

eng

Pagination

30

Informations de copyright

Copyright: © 2024 The Author(s). Published by IMR Press.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

Auteurs

Lars Saemann (L)

Department of Cardiac Surgery, University of Halle, 06120 Halle, Germany.
Department of Cardiac Surgery, University of Heidelberg, 69120 Heidelberg, Germany.
ORCID: 0000-0003-1516-3286

Alina Zubarevich (A)

Department of Cardiac Surgery, University of Heidelberg, 69120 Heidelberg, Germany.
Department of Cardiac-, Thoracic-, Transplantation and Vascular Surgery, Hannover Medical School, 30625 Hannover, Germany.

Folker Wenzel (F)

Faculty Medical and Life Sciences, Furtwangen University, 78054 Villingen-Schwenningen, Germany.

Jasmin Soethoff (J)

Department of Cardiac Surgery, University of Heidelberg, 69120 Heidelberg, Germany.

Sevil Korkmaz-Icöz (S)

Department of Cardiac Surgery, University of Halle, 06120 Halle, Germany.
Department of Cardiac Surgery, University of Heidelberg, 69120 Heidelberg, Germany.

Fabio Hoorn (F)

Department of Cardiac Surgery, University of Heidelberg, 69120 Heidelberg, Germany.
Department of Cardiac-, Thoracic-, Transplantation and Vascular Surgery, Hannover Medical School, 30625 Hannover, Germany.

Matthias Karck (M)

Department of Cardiac Surgery, University of Heidelberg, 69120 Heidelberg, Germany.

Andreas Simm (A)

Department of Cardiac Surgery, University of Halle, 06120 Halle, Germany.

Gábor Szabó (G)

Department of Cardiac Surgery, University of Halle, 06120 Halle, Germany.
Department of Cardiac Surgery, University of Heidelberg, 69120 Heidelberg, Germany.

Gábor Veres (G)

Department of Cardiac Surgery, University of Halle, 06120 Halle, Germany.
Department of Cardiac Surgery, University of Heidelberg, 69120 Heidelberg, Germany.

Classifications MeSH