Interdisciplinary perspectives on multimorbidity in Africa: Developing an expanded conceptual model.


Journal

PLOS global public health
ISSN: 2767-3375
Titre abrégé: PLOS Glob Public Health
Pays: United States
ID NLM: 9918283779606676

Informations de publication

Date de publication:
2024
Historique:
received: 26 10 2023
accepted: 11 06 2024
medline: 30 7 2024
pubmed: 30 7 2024
entrez: 30 7 2024
Statut: epublish

Résumé

Multimorbidity is an emerging challenge for health systems globally. It is commonly defined as the co-occurrence of two or more chronic conditions in one person, but its meaning remains a lively area of academic debate, and the utility of the concept beyond high-income settings is uncertain. This article presents the findings from an interdisciplinary research initiative that drew together 60 academic and applied partners working in 10 African countries to answer the questions: how useful is the concept of multimorbidity within Africa? Can the concept be adapted to context to optimise its transformative potentials? During a three-day concept-building workshop, we investigated how the definition of multimorbidity was understood across diverse disciplinary and regional perspectives, evaluated the utility and limitations of existing concepts and definitions, and considered how to build a more context-sensitive, cross-cutting description of multimorbidity. This iterative process was guided by the principles of grounded theory and involved focus- and whole-group discussions during the workshop, thematic coding of workshop discussions, and further post-workshop development and refinement. Three thematic domains emerged from workshop discussions: the current focus of multimorbidity on constituent diseases; the potential for revised concepts to centre the priorities, needs, and social context of people living with multimorbidity (PLWMM); and the need for revised concepts to respond to varied conceptual priorities amongst stakeholders. These themes fed into the development of an expanded conceptual model that centres the catastrophic impacts multimorbidity can have for PLWMM, families and support structures, service providers, and health systems.

Identifiants

pubmed: 39078807
doi: 10.1371/journal.pgph.0003434
pii: PGPH-D-23-02043
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e0003434

Informations de copyright

Copyright: © 2024 Dixon et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

Auteurs

Justin Dixon (J)

The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.
Department of Global Health and Development, London School of Hygiene and Tropical Medicine, London, United Kingdom.

Ben Morton (B)

Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi.
Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.

Misheck J Nkhata (MJ)

SHLS Nursing and Midwifery, Teesside University, Middlesborough, United Kingdom.

Alan Silman (A)

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Oxford University, Oxford, United Kingdom.

Ibrahim G Simiyu (IG)

Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.

Stephen A Spencer (SA)

Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi.
Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.

Myrna Van Pinxteren (M)

Faculty of Health Sciences, Department of Medicine and Chronic Disease Initiative for Africa, University of Cape Town, Cape Town, South Africa.

Christopher Bunn (C)

Malawi Epidemiology and Intervention Research Unit, Lilongwe, Malawi.
College of Social Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom.

Claire Calderwood (C)

The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.
Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, United Kingdom.

Clare I R Chandler (CIR)

Department of Global Health and Development, London School of Hygiene and Tropical Medicine, London, United Kingdom.

Edith Chikumbu (E)

Malawi Epidemiology and Intervention Research Unit, Lilongwe, Malawi.

Amelia C Crampin (AC)

Malawi Epidemiology and Intervention Research Unit, Lilongwe, Malawi.
Department of Population Health, London School of Hygiene & Tropical Medicine, London, United Kingdom.
School of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom.

John R Hurst (JR)

UCL Respiratory, University College London, London, United Kingdom.

Modou Jobe (M)

MRC Unit The Gambia at LSHTM, Banjul, The Gambia.

Andre Pascal Kengne (AP)

Non-communicable Diseases Research Unit, South African Medical Research Council, Cape Town, Durban, South Africa.

Naomi S Levitt (NS)

Faculty of Health Sciences, Department of Medicine and Chronic Disease Initiative for Africa, University of Cape Town, Cape Town, South Africa.

Mosa Moshabela (M)

School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.

Mayowa Owolabi (M)

Centre for Genomic and Precision Medicine, University of Ibadan, Ibadan, Nigeria.

Nasheeta Peer (N)

Non-communicable Diseases Research Unit, South African Medical Research Council, Cape Town, Durban, South Africa.

Nozgechi Phiri (N)

Malawi Epidemiology and Intervention Research Unit, Lilongwe, Malawi.

Sally J Singh (SJ)

Department of Respiratory Sciences, University of Leicester, Leicester, United Kingdom.

Tsaone Tamuhla (T)

South African National Bioinformatics Institute, University of the Western Cape, Cape Town, South Africa.

Mandikudza Tembo (M)

The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.
Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, United Kingdom.

Nicki Tiffin (N)

South African National Bioinformatics Institute, University of the Western Cape, Cape Town, South Africa.

Eve Worrall (E)

Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.

Nateiya M Yongolo (NM)

Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Kilimanjaro Clinical Research Institute, Moshi, Tanzania.

Gift T Banda (GT)

Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi.
Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.

Fanuel Bickton (F)

Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi.
Department of Rehabilitation Sciences, The Kamuzu University of Health Sciences, Blantyre, Malawi.

Abbi-Monique Mamani Bilungula (AM)

Department of Physical Medicine and Rehabilitation, University of Kinshasa, Kinshasa, Democratic Republic of Congo.

Edna Bosire (E)

Brain and Mind Institute, Aga Khan University, Nairobi, Kenya.
SAMRC Developmental Pathways for Health Research Unit, University of the Witwatersrand, Johannesburg, South Africa.

Marlen S Chawani (MS)

Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi.
Health Economics and Policy Unit, The Kamuzu University of Health Sciences, Blantyre, Malawi.

Beatrice Chinoko (B)

Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi.

Mphatso Chisala (M)

Malawi Epidemiology and Intervention Research Unit, Lilongwe, Malawi.

Jonathan Chiwanda (J)

Department of Non-communicable Diseases, Ministry of Health, Lilongwe, Malawi.

Sarah Drew (S)

Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.

Lindsay Farrant (L)

Faculty of Health Sciences, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa.

Rashida A Ferrand (RA)

The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.
Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, United Kingdom.

Mtisunge Gondwe (M)

Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi.
Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.

Celia L Gregson (CL)

The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.
Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.

Richard Harding (R)

Florence Nightingale Faculty of Nursing Midwifery and Palliative Care, Cicely Saunders Institute, King's College London, London, United Kingdom.

Dan Kajungu (D)

Makerere University Centre for Health and Population Research, Makerere University, Kampala, Uganda.

Stephen Kasenda (S)

Malawi Epidemiology and Intervention Research Unit, Lilongwe, Malawi.

Winceslaus Katagira (W)

Makerere Lung Institute, Makerere University, Kampala, Uganda.

Duncan Kwaitana (D)

Department of Family Medicine, The Kamuzu University of Health Sciences, Blantyre, Malawi.

Emily Mendenhall (E)

Edmund A. Walsh School of Foreign Service, Georgetown University, Washington, DC, United States of America.

Adwoa Bemah Boamah Mensah (ABB)

Department of Nursing, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Modai Mnenula (M)

College of Medicine, University of Malawi, Blantyre, Malawi.

Lovemore Mupaza (L)

Island Hospice and Healthcare, Harare, Zimbabwe.

Maud Mwakasungula (M)

Malawi NCD Alliance, Lilongwe, Malawi.

Wisdom Nakanga (W)

Malawi Epidemiology and Intervention Research Unit, Lilongwe, Malawi.
Deanery of Clinical Sciences, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, United Kingdom.

Chiratidzo Ndhlovu (C)

Internal Medicine Unit, Faculty of Medicine and Health Sciences, University of Zimbabwe, Harare, Zimbabwe.

Kennedy Nkhoma (K)

Florence Nightingale Faculty of Nursing Midwifery and Palliative Care, Cicely Saunders Institute, King's College London, London, United Kingdom.

Owen Nkoka (O)

Malawi Epidemiology and Intervention Research Unit, Lilongwe, Malawi.
College of Social Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom.

Edwina Addo Opare-Lokko (EA)

Greater Accra Regional Hospital, Faculty of Family Medicine, Ghana College of Physicians and Surgeons, Accra, Ghana.

Jacob Phulusa (J)

Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi.

Alison Price (A)

Malawi Epidemiology and Intervention Research Unit, Lilongwe, Malawi.
Department of Population Health, London School of Hygiene & Tropical Medicine, London, United Kingdom.

Jamie Rylance (J)

Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi.
Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.

Charity Salima (C)

Achikondi Women and Community Friendly Health Services, Lilongwe, Malawi.

Sangwani Salimu (S)

Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi.
Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.

Joachim Sturmberg (J)

School of Medicine and Public Health, Faculty of Health and Medicine, University of Newcastle, Newcastle, Australia.
International Society of Systems and Complexity Sciences for Health, Waitsfield, VT, United States of America.

Elizabeth Vale (E)

University of the Witwatersrand, Johannesburg, South Africa.

Felix Limbani (F)

Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi.

Classifications MeSH