Screening for tropical and imported infections in migrant kidney transplant candidates from the kidney transplant access consultation.

Imported infections Infecciones importadas Kidney transplant Serology Serología Trasplante renal Tropical Tropicales

Journal

Nefrologia
ISSN: 2013-2514
Titre abrégé: Nefrologia (Engl Ed)
Pays: Spain
ID NLM: 101778581

Informations de publication

Date de publication:
29 Jul 2024
Historique:
received: 03 03 2023
revised: 05 10 2023
accepted: 05 10 2023
medline: 31 7 2024
pubmed: 31 7 2024
entrez: 30 7 2024
Statut: aheadofprint

Résumé

Kidney transplantation (KT) should be postponed in those people with active bacterial, fungal, viral and parasitic processes, since these must be treated and resolved previously. The objective of this study is to present the screening circuit implemented by the Nephrology clinic and describe the prevalence of tropical and imported infections in KT candidates born or coming from endemic areas. Descriptive cross-sectional study, carried out in 2021. Sociodemographic and clinical variables, serological data of general infections and specific tests of tropical infectious diseases were collected. A descriptive analysis of the data was carried out. 67 TR candidates from Latin America (32.8%), North Africa (22.4%), Sub-Saharan Africa (14.9%) and Asia (29.9%) were included. 68.7% were men and the mean age was 48.9 ± 13.5 years. After the general and specific studies, 42 (62.7%) patients were referred to the Infectious Diseases Service to complete this study or indicate treatment. 35.8% of the patients had eosinophilia, and in one case parasites were detected in feces at the time of the study. Serology for strongyloidiasis was positive in 18 (26.9%) cases, while positive serology for other tropical infections was hardly detected. 34.3% of patients had latent tuberculosis infection. The prevalence of tropical and imported infections in migrant candidates for RT was low, except for strongyloidiasis and latent tuberculosis infection. Its detection and treatment are essential to avoid serious complications in post-TR. To this end, the implementation of an interdisciplinary screening program from the KT access consultation is feasible, necessary and useful.

Sections du résumé

BACKGROUND AND OBJECTIVE OBJECTIVE
Kidney transplantation (KT) should be postponed in those people with active bacterial, fungal, viral and parasitic processes, since these must be treated and resolved previously. The objective of this study is to present the screening circuit implemented by the Nephrology clinic and describe the prevalence of tropical and imported infections in KT candidates born or coming from endemic areas.
MATERIALS AND METHODS METHODS
Descriptive cross-sectional study, carried out in 2021. Sociodemographic and clinical variables, serological data of general infections and specific tests of tropical infectious diseases were collected. A descriptive analysis of the data was carried out.
RESULTS RESULTS
67 TR candidates from Latin America (32.8%), North Africa (22.4%), Sub-Saharan Africa (14.9%) and Asia (29.9%) were included. 68.7% were men and the mean age was 48.9 ± 13.5 years. After the general and specific studies, 42 (62.7%) patients were referred to the Infectious Diseases Service to complete this study or indicate treatment. 35.8% of the patients had eosinophilia, and in one case parasites were detected in feces at the time of the study. Serology for strongyloidiasis was positive in 18 (26.9%) cases, while positive serology for other tropical infections was hardly detected. 34.3% of patients had latent tuberculosis infection.
CONCLUSIONS CONCLUSIONS
The prevalence of tropical and imported infections in migrant candidates for RT was low, except for strongyloidiasis and latent tuberculosis infection. Its detection and treatment are essential to avoid serious complications in post-TR. To this end, the implementation of an interdisciplinary screening program from the KT access consultation is feasible, necessary and useful.

Identifiants

pubmed: 39079886
pii: S2013-2514(24)00157-3
doi: 10.1016/j.nefroe.2024.07.006
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2023 Sociedad Española de Nefrología. Published by Elsevier España, S.L.U. All rights reserved.

Auteurs

Guillermo Pedreira-Robles (G)

Servicio de Nefrología, Parc de Salut Mar, Hospital del Mar, Barcelona, Spain; ESIMar (Escuela Superior de Enfermería del Mar), Parc de Salut Mar, Centro adscrito a la Universitat Pompeu Fabra, Barcelona, Spain; SDHEd (Grupo de Investigación en Determinantes Sociales y Educación en Salud), IMIM (Instituto Hospital del Mar de Investigaciones Médicas), Barcelona, Spain.

Anna Bach-Pascual (A)

Servicio de Nefrología, Parc de Salut Mar, Hospital del Mar, Barcelona, Spain.

Silvia Collado-Nieto (S)

Servicio de Nefrología, Parc de Salut Mar, Hospital del Mar, Barcelona, Spain; Grupo de Investigación en Nefropatías, Instituto Hospital del Mar de Investigaciones Médicas (IMIM), RD21/0005/0022 (ISCIII MRR RICORS), Barcelona, Spain.

Eduardo Padilla (E)

Laboratorio de Referencia de Catalunya, Barcelona, Spain.

Carla Burballa (C)

Servicio de Nefrología, Parc de Salut Mar, Hospital del Mar, Barcelona, Spain; Grupo de Investigación en Nefropatías, Instituto Hospital del Mar de Investigaciones Médicas (IMIM), RD21/0005/0022 (ISCIII MRR RICORS), Barcelona, Spain.

Carlos Arias-Cabrales (C)

Servicio de Nefrología, Parc de Salut Mar, Hospital del Mar, Barcelona, Spain; Grupo de Investigación en Nefropatías, Instituto Hospital del Mar de Investigaciones Médicas (IMIM), RD21/0005/0022 (ISCIII MRR RICORS), Barcelona, Spain.

Dolores Redondo-Pachón (D)

Servicio de Nefrología, Parc de Salut Mar, Hospital del Mar, Barcelona, Spain; Grupo de Investigación en Nefropatías, Instituto Hospital del Mar de Investigaciones Médicas (IMIM), RD21/0005/0022 (ISCIII MRR RICORS), Barcelona, Spain.

Francisca Sánchez (F)

Servicio de Enfermedades Infecciosas, Instituto Hospital del Mar de Investigaciones Médicas (IMIM), Universitat Pompeu Fabra, Hospital del Mar, Barcelona, Spain.

Juan Pablo Horcajada (JP)

Servicio de Enfermedades Infecciosas, Instituto Hospital del Mar de Investigaciones Médicas (IMIM), Universitat Pompeu Fabra, Hospital del Mar, Barcelona, Spain.

Julio Pascual (J)

Servicio de Nefrología, Parc de Salut Mar, Hospital del Mar, Barcelona, Spain; Grupo de Investigación en Nefropatías, Instituto Hospital del Mar de Investigaciones Médicas (IMIM), RD21/0005/0022 (ISCIII MRR RICORS), Barcelona, Spain; Servicio de Nefrología, Hospital Universitario 12 de Octubre, Madrid, Spain.

Marta Crespo (M)

Servicio de Nefrología, Parc de Salut Mar, Hospital del Mar, Barcelona, Spain; Grupo de Investigación en Nefropatías, Instituto Hospital del Mar de Investigaciones Médicas (IMIM), RD21/0005/0022 (ISCIII MRR RICORS), Barcelona, Spain.

Judit Villar-García (J)

Servicio de Enfermedades Infecciosas, Instituto Hospital del Mar de Investigaciones Médicas (IMIM), Universitat Pompeu Fabra, Hospital del Mar, Barcelona, Spain.

María José Pérez-Sáez (MJ)

Servicio de Nefrología, Parc de Salut Mar, Hospital del Mar, Barcelona, Spain; Grupo de Investigación en Nefropatías, Instituto Hospital del Mar de Investigaciones Médicas (IMIM), RD21/0005/0022 (ISCIII MRR RICORS), Barcelona, Spain. Electronic address: mperezsaez@psmar.cat.

Classifications MeSH