Genome-wide association study of trace elements in maize kernels.
Candidate genes
GWAS
Haplotype analysis
Maize kernel
QTLs
Trace element
Journal
BMC plant biology
ISSN: 1471-2229
Titre abrégé: BMC Plant Biol
Pays: England
ID NLM: 100967807
Informations de publication
Date de publication:
30 Jul 2024
30 Jul 2024
Historique:
received:
27
05
2024
accepted:
15
07
2024
medline:
31
7
2024
pubmed:
31
7
2024
entrez:
30
7
2024
Statut:
epublish
Résumé
Maize (Zea mays L.), a staple food and significant economic crop, is enriched with riboflavin, micronutrients and other compounds that are beneficial for human health. As emphasis on the nutritional quality of crops increases maize research has expanded to focus on both yield and quality. This study exploreed the genetic factors influencing micronutrient levels in maize kernels through a comprehensive genome-wide association study (GWAS). We utilized a diverse panel of 244 inbred maize lines and approximately 3 million single nucleotide polymorphisms (SNPs) to investigate the accumulation of essential and trace elements including cadmium (Cd), cobalt (Co), copper (Cu), nickel (Ni), selenium (Se) and zinc (Zn). Our analysis identified 842 quantitative trait loci (QTLs), with 12 QTLs shared across multiple elements and pinpointed 524 potential genes within a 100 kb radius of these QTLs. Notably ZmHMA3 has emerged as a key candidate gene previously reported to influence the Cd accumulation. We highlighted ten pivotal genes associated with trace element transport including those encoding heavy metal ATPases, MYB transcription factors, ABC transporters and other crucial proteins involved in metal handling. Additionally, haplotype analysis revealed that eight inbred linesaccumulated relatively high levels of beneficial elements while harmful elements were minimized. These findings elucidate the genetic mechanisms underlying trace element accumulation in maize kernels and provide a foundation for the breeding of nutritionally enhanced maize varieties.
Identifiants
pubmed: 39080529
doi: 10.1186/s12870-024-05419-4
pii: 10.1186/s12870-024-05419-4
doi:
Substances chimiques
Trace Elements
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
724Subventions
Organisme : the Basic and Applied Basic Research Fund of Guangdong Province
ID : 2022A1515110760
Organisme : the GDAS' Project of Science and Technology Development
ID : 2022GDASZH-2022010102
Organisme : the National Natural Science Foundation of China
ID : 32072027
Organisme : the Guangdong Province Special Projects in Key Fields of Ordinary Colleges and Universities, the Guangdong Province Key Construction Discipline Research Ability Enhancement Project
ID : 2022ZDJS023
Organisme : the Special Project for Rural Revitalization Strategy in Guangdong Provincethe Special Project for Rural Revitalization Strategy in Guangdong Province
ID : 2022-NPY-00-023-5
Informations de copyright
© 2024. The Author(s).
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