Extranodal natural killer/T-cell lymphoma with tonsil involvement: a case report.
Humans
Female
Adolescent
Lymphoma, Extranodal NK-T-Cell
/ pathology
Tonsillar Neoplasms
/ pathology
Antineoplastic Combined Chemotherapy Protocols
/ therapeutic use
Palatine Tonsil
/ pathology
Tonsillitis
/ pathology
Follow-Up Studies
Gene Rearrangement, T-Lymphocyte
Pharyngitis
/ pathology
Vincristine
/ therapeutic use
Tomography, X-Ray Computed
Cyclophosphamide
/ therapeutic use
Case report
ENKTL
Natural killer/T-cell lymphoma
SMILE chemotherapy
Tonsils
Journal
BMC oral health
ISSN: 1472-6831
Titre abrégé: BMC Oral Health
Pays: England
ID NLM: 101088684
Informations de publication
Date de publication:
30 Jul 2024
30 Jul 2024
Historique:
received:
05
02
2024
accepted:
06
06
2024
medline:
31
7
2024
pubmed:
31
7
2024
entrez:
31
7
2024
Statut:
epublish
Résumé
Extranodal natural killer/T-cell lymphoma (ENKTL) with tonsil involvement is not common, especially in children. A 13-year-old girl presented with an unexplained sore throat for more than 2 months, together with intermittent fever and suppurative tonsilitis. Nasopharyngoscopy revealed a pharyngeal mass. Enhanced computed tomography (CT) scan showed tonsillar hypertrophy and punctate calcification. Chronic pyogenic granulomatous inflammation with pseudoepithelial squamous epithelial hyperplasia was observed in left tonsil, and pyogenic granulomatous inflammation and a small number of T-lymphoid cells were detected in the right tonsil. The immunohistochemical results showed CD2 We presented a rare case of ENKTL with tonsil involvement in a child. The patient showed complete response to the SMILE chemotherapy with no recurrence.
Sections du résumé
BACKGROUND
BACKGROUND
Extranodal natural killer/T-cell lymphoma (ENKTL) with tonsil involvement is not common, especially in children.
CASE PRESENTATION
METHODS
A 13-year-old girl presented with an unexplained sore throat for more than 2 months, together with intermittent fever and suppurative tonsilitis. Nasopharyngoscopy revealed a pharyngeal mass. Enhanced computed tomography (CT) scan showed tonsillar hypertrophy and punctate calcification. Chronic pyogenic granulomatous inflammation with pseudoepithelial squamous epithelial hyperplasia was observed in left tonsil, and pyogenic granulomatous inflammation and a small number of T-lymphoid cells were detected in the right tonsil. The immunohistochemical results showed CD2
CONCLUSION
CONCLUSIONS
We presented a rare case of ENKTL with tonsil involvement in a child. The patient showed complete response to the SMILE chemotherapy with no recurrence.
Identifiants
pubmed: 39080655
doi: 10.1186/s12903-024-04452-x
pii: 10.1186/s12903-024-04452-x
doi:
Substances chimiques
Vincristine
5J49Q6B70F
Cyclophosphamide
8N3DW7272P
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
867Informations de copyright
© 2024. The Author(s).
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